Results 241 to 250 of about 51,117 (269)
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International journal of peptide and protein research, 1993
Synthesized beta 1- and beta 2-pentapeptide sequences corresponding to published adrenoceptor transmembrane activation site subtypes were investigated in vitro for selectivity in association for drug ligands of known selectivity. Both nuclear magnetic resonance spectroscopy and molecular mechanics demonstrated that structural differences among the ...
W F, Schmidt +5 more
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Synthesized beta 1- and beta 2-pentapeptide sequences corresponding to published adrenoceptor transmembrane activation site subtypes were investigated in vitro for selectivity in association for drug ligands of known selectivity. Both nuclear magnetic resonance spectroscopy and molecular mechanics demonstrated that structural differences among the ...
W F, Schmidt +5 more
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European Journal of Clinical Investigation, 1994
Abstract. To evaluate the effects of multiple β‐adrenergic stimulations on pulmonary surfactant phospholipids, perfused lungs from β‐adrenergic primed and non‐primed rats were challenged with the β‐agonist terbutaline in vitro. Cell‐free lung lavage, lavagable alveolar cells and lung tissue were analysed for phospholipid content and incorporation of ...
W, Bernhard, B, Müller, P, Von Wichert
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Abstract. To evaluate the effects of multiple β‐adrenergic stimulations on pulmonary surfactant phospholipids, perfused lungs from β‐adrenergic primed and non‐primed rats were challenged with the β‐agonist terbutaline in vitro. Cell‐free lung lavage, lavagable alveolar cells and lung tissue were analysed for phospholipid content and incorporation of ...
W, Bernhard, B, Müller, P, Von Wichert
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European Journal of Biochemistry, 1979
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
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When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
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Comptes rendus des seances de la Societe de biologie et de ses filiales, 1996
The variations in the intracellular free calcium concentration, [Ca2+]i, have been studied in isolated acini of rat parotid gland with a fluorescent probe, fura-2. In unstimulated acini, [Ca2+]i amounted to a basal value of 180 nM. Isoproterenol used at a concentration of 200 microM, in the presence of a beta-adrenergic blocker, caused a net increase ...
A, Sezan, D, Eboué, B, Rossignol
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The variations in the intracellular free calcium concentration, [Ca2+]i, have been studied in isolated acini of rat parotid gland with a fluorescent probe, fura-2. In unstimulated acini, [Ca2+]i amounted to a basal value of 180 nM. Isoproterenol used at a concentration of 200 microM, in the presence of a beta-adrenergic blocker, caused a net increase ...
A, Sezan, D, Eboué, B, Rossignol
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Drug design and delivery, 1989
The electrostatic molecular potential (EMP) of model compounds (isoproterenol and four of its analogs) with agonist activity on the beta-adrenergic receptor was investigated, at the SCF-MO ab initio level. A method was developed to calculate the drug-receptor interaction energy (delta E) for these compounds, and the EMP and delta E values were compared
B, Macchia, A, Martinelli
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The electrostatic molecular potential (EMP) of model compounds (isoproterenol and four of its analogs) with agonist activity on the beta-adrenergic receptor was investigated, at the SCF-MO ab initio level. A method was developed to calculate the drug-receptor interaction energy (delta E) for these compounds, and the EMP and delta E values were compared
B, Macchia, A, Martinelli
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Physiology
INTRODUCTION: Estrogen is protective against weight gain via mechanisms mediated by adipocyte-specific receptors. Specifically, estrogen receptor beta (ERb) activation is non-feminizing and increases adipocyte mitochondrial activity leading to increased energy expenditure (EE ...
John Cullen +7 more
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INTRODUCTION: Estrogen is protective against weight gain via mechanisms mediated by adipocyte-specific receptors. Specifically, estrogen receptor beta (ERb) activation is non-feminizing and increases adipocyte mitochondrial activity leading to increased energy expenditure (EE ...
John Cullen +7 more
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BJOG : an international journal of obstetrics and gynaecology, 2001
To compare the effectiveness and safety of the oxytocin antagonist atosiban with conventional beta-adrenergic agonist (beta-agonist) therapy in the treatment of preterm labour.Three multinational, multicentre, double-blind, randomised, controlled trials. Setting Hospitals in Australia, Canada, Czech Republic, Denmark, France, Israel, Sweden, and the UK.
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To compare the effectiveness and safety of the oxytocin antagonist atosiban with conventional beta-adrenergic agonist (beta-agonist) therapy in the treatment of preterm labour.Three multinational, multicentre, double-blind, randomised, controlled trials. Setting Hospitals in Australia, Canada, Czech Republic, Denmark, France, Israel, Sweden, and the UK.
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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2022
Hua Kuang, Chuanlai Xu, Xinxin Xu
exaly
Hua Kuang, Chuanlai Xu, Xinxin Xu
exaly