Results 221 to 230 of about 116,135 (274)

Selective regulation of beta-1 and beta-2 adrenergic receptors by atypical agonists.

Journal of Pharmacology and Experimental Therapeutics, 1985
The interactions of the atypical agonists pindolol and celiprolol with beta adrenergic receptors were compared with those of the full agonist, isoproterenol.
Kim A. Neve, D. Barrett, Perry B. Molinoff   +2 more
semanticscholar   +1 more source

[The effect of adrenergic beta agonists on morbidity and mortality of asthma].

Presse medicale (Paris, France : 1983), 1993
The frequency and severity of asthma are increasing, and since 1960 two "epidemics" of deaths have occurred. During the first one, in the 1960's, a beta-adrenergic agonist with low specificity administered in high doses was blamed and usually exonerated.
J, Bousquet, P, Godard, F B, Michel
openaire   +1 more source

Response to inhaled beta-agonist in a patient receiving beta-adrenergic blockers.

Archives of internal medicine, 1984
A 52-year-old man receiving long-term hemodialysis and a beta-adrenergic blocker for hypertension had symptoms of acute bronchospasm when exposed to a new hemodialyzer. Resistant to two doses of subcutaneous epinephrine (1 mL of 1:1000 dilution) and one intravenous dose of aminophylline (250 mg), the bronchospasm was rapidly relieved by metaproterenol ...
A P, Lundin, B, Pilkington, B G, Delano, E A, Friedman   +3 more
openaire   +1 more source

β-Adrenergic receptor polymorphisms: relationship to the β-agonist controversy and clinical implications

Expert Opinion on Pharmacotherapy, 2007
Aspects of the 'beta-agonist controversy' have recently re-emerged with the publication of data implicating the long-acting beta-agonist salmeterol in increased mortality from asthma. The reasons underlying the adverse effects of beta2-agonists as a class are unclear.
openaire   +2 more sources

Chemical Grafting of Molecularly Imprinted Homopolymers to the Surface of Microplates. Application of Artificial Adrenergic Receptor in Enzyme-Linked Assay for β-Agonists Determination

Analytical Chemistry, 2000
A technique for coating of microplate wells with a molecularly imprinted polymer (MIP), specific for epinephrine, is presented. 3-Aminophenylboronic acid was polymerized in the presence of epinephrine using oxidation of the monomer by ammonium persulfate.
S A, Piletsky, E V, Piletska, B, Chen, K, Karim, D, Weston, G, Barrett, P, Lowe, A P, Turner   +7 more
openaire   +2 more sources

Characterization of cell-surface ?-adrenergic ([3H]CGP-12177) binding in adult rat ventricular myocytes: lack of regulation by ?-agonists at physiological concentrations

Pfl�gers Archiv European Journal of Physiology, 1992
The major focus of this paper is the characterization and quantification of rat cardiomyocyte, cell-surface beta-adrenergic receptors labelled with the hydrophilic radioligand [3H]CGP-12177. The ventricular cardiomyocytes used in these experiments have previously been extensively studied in our laboratory and confirmed to be functionally compatible ...
M, Horackova, M, Wilkinson
openaire   +2 more sources

β‐adrenergic priming of rats in vivo modulates the effect of β‐agonist in vitro on surfactant phospholipid metabolism of isolated lungs

European Journal of Clinical Investigation, 1994
Abstract. To evaluate the effects of multiple β‐adrenergic stimulations on pulmonary surfactant phospholipids, perfused lungs from β‐adrenergic primed and non‐primed rats were challenged with the β‐agonist terbutaline in vitro. Cell‐free lung lavage, lavagable alveolar cells and lung tissue were analysed for phospholipid content and incorporation of ...
W, Bernhard, B, Müller, P, Von Wichert
openaire   +2 more sources

Evidence for a Second Desensitized State of β‐Adrenergic Receptor with Low Affinity for β‐Antagonists and Normal Reactivity towards β‐Agonists in Adipocyte Membranes Previously Exposed to β‐Antagonists

European Journal of Biochemistry, 1979
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Y, Giudicelli, D, Lacasa, B, Agli
openaire   +2 more sources

[Effect of adrenergic beta-agonist on intracellular free calcium concentration in isolated acini of the parotid gland in rats].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1996
The variations in the intracellular free calcium concentration, [Ca2+]i, have been studied in isolated acini of rat parotid gland with a fluorescent probe, fura-2. In unstimulated acini, [Ca2+]i amounted to a basal value of 180 nM. Isoproterenol used at a concentration of 200 microM, in the presence of a beta-adrenergic blocker, caused a net increase ...
A, Sezan, D, Eboué, B, Rossignol
openaire   +1 more source

Dual Treatment of a Beta 3 Adrenergic Receptor Agonist and a Novel Estrogen Receptor Beta Agonist on Body Composition, Metabolism, and Glucose Tolerance in Obese Male Mice

Physiology
INTRODUCTION: Estrogen is protective against weight gain via mechanisms mediated by adipocyte-specific receptors. Specifically, estrogen receptor beta (ERb) activation is non-feminizing and increases adipocyte mitochondrial activity leading to increased energy expenditure (EE ...
John Cullen, Dusti Shay, Kayla Burkle, Trinity Cunningham, Samantha Marquis, Samuel Kulp, Christopher Coss, Victoria Vieira-Potter   +7 more
openaire   +1 more source