Results 1 to 10 of about 47,080 (153)

Persistent bothersome urinary frequency following stereotactic body radiation therapy for clinically localized prostate cancer: rationale for prophylactic β3-agonist in men with elevated baseline international prostate symptom scores [PDF]

Frontiers in Oncology
IntroductionStereotactic body radiation therapy (SBRT) for clinically localized prostate cancer has been associated with prolonged acute obstructive and irritative lower urinary tract symptoms (LUTS).
Jennifer Zack, Min Ji Koh, Emily Lindbloom, Timothy O’Connor, Kelly Gaudian, Alan Zwart, Malika Danner, Deepak Kumar, Simeng Suy, Ryan Hankins, Sean Collins   +10 more
doaj   +2 more sources

Respiratory outcomes of adrenergic beta-antagonists in patients undergoing tracheal extubation: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Braz J Anesthesiol
Bendaham LCAR, Neto APM, Faria HS, Filho ARDSO, Ferreira CHO, Cunha MDSK, Soares VG, Gonçalves OR, Sobral MVS, Doma M, Grutcki DM, Mendonça FT.   +11 more
europepmc   +3 more sources

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]

, 2011
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle, B Isin, B Isin, B Isin, Basak Isin, BK Kobilka, BK Kobilka, C Gales, CD Strader, CD Strader, CD Strader, DL Farrens, DM Rosenbaum, DM Rosenbaum, DS Han, E Reiter, FZ Chung, G Liapakis, G Liapakis, G Swaminath, G Swaminath, Guillermina Estiu, GV Paolini, HW Choe, I Bahar, JA Javitch, JC Phillips, JE Olsson, JJ Liu, JP Overington, K Palczewski, K Wieland, KA Reynolds, L Shi, LM Luttrell, LS Barak, M Arakawa, M Azzi, MA Yildirim, MP Bokoch, MS Johnson, O Fritze, Olaf Wiest, P Ghanouni, PG Strange, R Nygaard, R Seifert, RA Friesner, RA Friesner, RO Dror, S Ahuja, S Bhattacharya, S Ludeke, SA Green, SG Rasmussen, SG Rasmussen, SG Rasmussen, T Palanche, TD Romo, U Gether, V Cherezov, X Deupi, X Yao, X Zhang, Zoltán N. Oltvai   +64 more
core   +10 more sources

Evaluation of the effects of Astragalus fasciculifolius hydroalcoholic extract on rat ileum contractions: The role of adrenergic, opioid, and nitric oxide receptors [PDF]

Future Natural Products, 2023
Background and aims: This study aimed to determine the effects of Astragalus fasciculifolius hydroalcoholic extract on rat ileum contractions: The role of adrenergic, opioid, and nitric oxide (NO) receptors. Methods: A.
Najmeh Asgharzadeh, Parisa Zamani, Fatemeh Azizi, Hossein Amini-Khoei, Elham Bijad, Mehrdad Shahrani-Korani   +5 more
doaj   +1 more source

Effects of cigarette smoking on the response of hypertensive patients to beta-adrenergic antagonists: a narrative review

Journal of Ideas in Health, 2022
Cigarette smoking is one of the hypertension risk factors which can adversely affect the quality of life. This review aimed to provide a brief overview of the link between smoking and hypertension.
Hala F. Kasim
doaj   +1 more source

The (--)[3H]dihydroalprenolol binding to rat adipocyte membranes: an explanation of curvilinear Scatchard plots and implications for quantitation of beta-adrenergic sites

Journal of Lipid Research, 1982
In rat adipocyte membranes, both beta-adrenergic agonists and beta-adrenergic antagonists competed with (--)[3H]dihydroalprenolol for high affinity (KD 2-4 nM) and low capacity binding sites.
E M Dax, J S Partilla, R I Gregerman
doaj   +1 more source

Beta-adrenergic receptor antagonism is proinflammatory and exacerbates neuroinflammation in a mouse model of Alzheimer's Disease

Neurobiology of Disease, 2020
Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one of ...
Andrew K. Evans, Pooneh M. Ardestani, Bitna Yi, Heui Hye Park, Rachel K. Lam, Mehrdad Shamloo   +5 more
doaj   +1 more source

Functional selectivity of GPCR-directed drug action through location bias. [PDF]

, 2017
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco, Huang, Bo, Irannejad, Roshanak, Mika, Delphine, Pessino, Veronica, von Zastrow, Mark, Wedegaertner, Philip B.   +6 more
core   +3 more sources

Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists.

Journal of Lipid Research, 1988
Beta-adrenergic receptors were characterized in human fat cell membranes using 125I-labeled cyanopindolol (125I-labeled CYP) and highly selective beta 1-antagonists.
P Mauriège, G De Pergola, M Berlan, M Lafontan   +3 more
doaj   +1 more source

Use of an ultrashort-acting selective β1-adrenergic receptor antagonist esmolol in ear, nose and throat surgery [PDF]

Scripta Medica, 2022
Background / Aim: The concept of general balanced anaesthesia was devised in order to assure cardiovascular stability and fast post-anaesthesia recovery.
Lončar-Stojiljković Dragana, Maksimović Žana M., Đurić Marko   +2 more
doaj   +1 more source