Results 1 to 10 of about 109,372 (346)

Evidence for a Second Desensitized State of β‐Adrenergic Receptor with Low Affinity for β‐Antagonists and Normal Reactivity towards β‐Agonists in Adipocyte Membranes Previously Exposed to β‐Antagonists [PDF]

European Journal of Biochemistry, 1979
When adipocyte membranes are successively exposed to (−)‐propranolol or (±)‐alprenolo1 at 25 or 4°C, repeatedly washed and then assayed for (−)‐[3H]dihydroalprenolol binding, the apparent number of β‐adrenergic binding sites is markedly decreased. Induction of this peculiar type of receptor desensitization does not require prolonged exposure of the ...
Daniètle Lacasa, Brigitte AGLl, Yves Giudicelli   +2 more
openaire   +3 more sources

Effects of cigarette smoking on the response of hypertensive patients to beta-adrenergic antagonists: a narrative review [PDF]

Journal of Ideas in Health, 2022
Cigarette smoking is one of the hypertension risk factors which can adversely affect the quality of life. This review aimed to provide a brief overview of the link between smoking and hypertension.
Hala F. Kasim
doaj   +3 more sources

Human fat cell beta-adrenergic receptors: beta-agonist-dependent lipolytic responses and characterization of beta-adrenergic binding sites on human fat cell membranes with highly selective beta 1-antagonists.

Journal of Lipid Research, 1988
Beta-adrenergic receptors were characterized in human fat cell membranes using 125I-labeled cyanopindolol (125I-labeled CYP) and highly selective beta 1-antagonists.
P Mauriège, G De Pergola, M Berlan, M Lafontan   +3 more
doaj   +2 more sources

Expression of inwardly rectifying potassium channels (GIRKs) and beta-adrenergic regulation of breast cancer cell lines [PDF]

BMC Cancer, 2004
Background Previous research has indicated that at various organ sites there is a subset of adenocarcinomas that is regulated by beta-adrenergic and arachidonic acid-mediated signal transduction pathways.
Cakir Yavuz, Yu Qiang, Plummer Howard K, Schuller Hildegard M   +3 more
doaj   +5 more sources

Topical administration of adrenergic receptor pharmaceutics and nerve growth factor [PDF]

Clinical Ophthalmology, 2010
Jena J SteinleDepartments of Ophthalmology and Anatomy and Neurobiology, Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USAAbstract: Topical application of nerve growth factor (NGF) and adrenergic receptor ...
Jena J Steinle
doaj   +3 more sources

Beta-Adrenergic Antagonists Attenuate Somatic and Aversive Signs of Opiate Withdrawal [PDF]

Neuropsychopharmacology, 1993
Glenda C. Harris, Gary Aston‐Jones
openalex   +2 more sources

Identifying Ligand Binding Conformations of the β2-Adrenergic Receptor by Using Its Agonists as Computational Probes [PDF]

, 2011
Recently available G-protein coupled receptor (GPCR) structures and biophysical studies suggest that the difference between the effects of various agonists and antagonists cannot be explained by single structures alone, but rather that the conformational
Ashley M. Buckle, B Isin, B Isin, B Isin, Basak Isin, BK Kobilka, BK Kobilka, C Gales, CD Strader, CD Strader, CD Strader, DL Farrens, DM Rosenbaum, DM Rosenbaum, DS Han, E Reiter, FZ Chung, G Liapakis, G Liapakis, G Swaminath, G Swaminath, Guillermina Estiu, GV Paolini, HW Choe, I Bahar, JA Javitch, JC Phillips, JE Olsson, JJ Liu, JP Overington, K Palczewski, K Wieland, KA Reynolds, L Shi, LM Luttrell, LS Barak, M Arakawa, M Azzi, MA Yildirim, MP Bokoch, MS Johnson, O Fritze, Olaf Wiest, P Ghanouni, PG Strange, R Nygaard, R Seifert, RA Friesner, RA Friesner, RO Dror, S Ahuja, S Bhattacharya, S Ludeke, SA Green, SG Rasmussen, SG Rasmussen, SG Rasmussen, T Palanche, TD Romo, U Gether, V Cherezov, X Deupi, X Yao, X Zhang, Zoltán N. Oltvai   +64 more
core   +10 more sources

Evaluation of the effects of Astragalus fasciculifolius hydroalcoholic extract on rat ileum contractions: The role of adrenergic, opioid, and nitric oxide receptors [PDF]

Future Natural Products, 2023
Background and aims: This study aimed to determine the effects of Astragalus fasciculifolius hydroalcoholic extract on rat ileum contractions: The role of adrenergic, opioid, and nitric oxide (NO) receptors. Methods: A.
Najmeh Asgharzadeh, Parisa Zamani, Fatemeh Azizi, Hossein Amini-Khoei, Elham Bijad, Mehrdad Shahrani-Korani   +5 more
doaj   +1 more source

Alpha-1 adrenergic receptor antagonists to prevent hyperinflammation and death from lower respiratory tract infection [PDF]

Elife 10 (2021): e61700, 2020
In severe viral pneumonia, including Coronavirus disease 2019 (COVID-19), the viral replication phase is often followed by hyperinflammation, which can lead to acute respiratory distress syndrome, multi-organ failure, and death. We previously demonstrated that alpha-1 adrenergic receptor ($\alpha_1$-AR) antagonists can prevent hyperinflammation and ...
arxiv   +1 more source

Analgesic Efficacy of Perioperative Esmolol as an Adjunct to Morphine in Mastectomy- A Prospective Observational Study [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Multimodal analgesia with opioids as the prime component is the mainstay of postoperative analgesia for mastectomy, which can lead to many opioid related unwanted side-effects.
JOSE TANIA, VADAKKOOT RAGHAVAN HEMA, Prabhakaran Vineetha   +2 more
doaj   +1 more source