Results 101 to 110 of about 115,479 (330)

Design of a new series of potent and selective beta-3 adrenergic receptor (β3-AdrR) antagonists for the treatment of acute decompensated heart failure

, 2022
Thuy-Anh Tran, Bryan Kramer, Young‐Jun Shin, Quyen‐Quyen Do, Brett R. Ullman, Vasudeva Sagi, John Adams, Yunqing Shi, Hsin-Hui Shu, David J. Unett, Joel Gatlin, Michael Morgan, Jaimie Reuter, A. C. Blackburn, Carleton R. Sage, Graeme Semple   +15 more
openalex   +1 more source

Bradycardia From a Non-selective Beta-Adrenergic Antagonist, Timolol, Applied Ophthalmologically for Glaucoma [PDF]

, 2022
Gedaliah May, Daniel Miller, Daniel Fuchs   +2 more
openalex   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Stevia Nonsweetener Fraction Displays an Insulinotropic Effect Involving Neurotransmission in Pancreatic Islets

International Journal of Endocrinology, 2018
Stevia rebaudiana (Bert.) Bertoni besides being a source of noncaloric sweeteners is also an important source of bioactive molecules. Many plant extracts, mostly obtained with ethyl acetate solvent, are rich in polyphenol compounds that present ...
Silvano Piovan, Audrei Pavanello, Giuliana Maria Ledesma Peixoto, Camila Cristina Ianoni Matiusso, Ana Maria Praxedes de Moraes, Isabela Peixoto Martins, Ananda Malta, Kesia Palma-Rigo, Claudinéia Conationi da Silva Franco, Paula Gimenez Milani, Antonio Sérgio Dacome, Silvio Claudio da Costa, Paulo Cezar de Freitas Mathias, Cecília Edna Mareze-Costa   +13 more
doaj   +1 more source

Cost-effectiveness of glaucoma management with monotherapy medications in Egypt

Journal of Advanced Pharmaceutical Technology & Research, 2017
Glaucoma is a serious chronic ophthalmic disease since it causes irreversible visual disability if untreated can lead to blindness. Treatment options include medications (classified into five major classes of drugs which are muscarinic cholinergic ...
Amal Abd-Elaal El-Khamery, Amir Ibrahim Mohamed, Hassan Eisa Hassan Swify, Alaa Ibrahim Mohamed   +3 more
doaj   +1 more source

Angiotensin II blockade and aortic-root dilation in Marfan's syndrome [PDF]

, 2008
Background: Progressive enlargement of the aortic root, leading to dissection, is the main cause of premature death in patients with Marfan's syndrome. Recent data from mouse models of Marfan's syndrome suggest that aortic-root enlargement is caused by ...
Brooke, Benjamin S., Dietz, Harry C., Habashi, Jennifer P., Judge, Daniel P., Loeys, Bart, Patel, Nishant   +5 more
core   +2 more sources

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Betabloqueador tópico pode determinar resultados inconclusivos no ecocardiograma sob estresse com dobutamina em pacientes com glaucoma Topical betablocker use can result in inconclusive dobutamine stress echocardiography in patients with glaucoma

Arquivos Brasileiros de Cardiologia, 2007
O ecocardiograma sob estresse com dobutamina é um método bem estabelecido para avaliar doença arterial coronária, cuja sensibilidade tem sido potencializada pela adição de atropina no final do protocolo.
Adriana Cordovil, Fernando Q. Matos, Orlando Campos Filho, Augusto Paranhos Jr., Ana Clara T. Rodrigues, Márcia V. Albernaz, Angelo A. V. de Paola, Antonio Carlos C. Carvalho   +7 more
doaj   +1 more source

The Postural Tachycardia Syndrome (POTS): Pathophysiology, Diagnosis & Management [PDF]

, 2006
Postural tachycardia syndrome (POTS), characterized by orthostatic tachycardia in the absence of orthostatic hypotension, has been the focus of increasing clinical interest over the last 15 years 1. Patients with POTS complain of symptoms of tachycardia,
Raj, Satish R
core   +1 more source

The future of pharmacogenetics in the treatment of heart failure [PDF]

, 2015
Heart failure is a common disease with high levels of morbidity and mortality. Current treatment comprises β-blockers, ACE inhibitors, aldosterone antagonists and diuretics.
Alex S Doney, Chim C Lang, Colin N Palmer, Green SA, Helen M Parry, Lanfear DE, Levy AP, Lillvis JH, Mesquita ET, Mohamed Subhan Anwar, Morrison AC, Muhammad Zaid Iskandar   +11 more
core   +2 more sources