Results 81 to 90 of about 37,264 (269)

QTC INTERVAL DURATION CLASS AND DRUG THERAPY OF PATIENCE IN A FIRST YEAR AFTER PACEMAKER IMPLANTATION

Journal of V. N. Karazin Kharkiv National University: Series Medicine, 2016
49 patients (28 female, 21 male) with implanted DDD/DDDR, VVI/VVIR and CRT pacemakers are investigated. Purpose frequency and dose rate of anticoagulants, antiplatelet agents, direct thrombin inhibitors, cardiac glycosides, amiodarone; ivabradine ...
M. S. Brynza, M. I. Yabluchansky
doaj  

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Late expression of alpha 2-adrenergic-mediated antilipolysis during differentiation of hamster preadipocytes.

Journal of Lipid Research, 1991
In order to study the ontogenesis of the beta- and alpha 2-adrenergic control of lipolysis during the adipose conversion process, a model based on preadipocytes isolated from the stromal-vascular fraction of hamster adipose tissue was developed.
JS Saulnier-Blache, M Dauzats, D Daviaud, D Gaillard, G Ailhaud, R Négrel, M Lafontan   +6 more
doaj   +1 more source

Assessment of Abuse Potential‐Related Effects of Oral Dried Kratom Leaf Powder in Healthy Normal Participants Following Single and Multiple Daily Doses

Drug Testing and Analysis, EarlyView.
In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe, Marilyn Huestis, Daniel Wang, Thomas Hudzik, John Bothmer, Jack Henningfield   +5 more
wiley   +1 more source

Cost-effectiveness of glaucoma management with monotherapy medications in Egypt

Journal of Advanced Pharmaceutical Technology & Research, 2017
Glaucoma is a serious chronic ophthalmic disease since it causes irreversible visual disability if untreated can lead to blindness. Treatment options include medications (classified into five major classes of drugs which are muscarinic cholinergic ...
Amal Abd-Elaal El-Khamery, Amir Ibrahim Mohamed, Hassan Eisa Hassan Swify, Alaa Ibrahim Mohamed   +3 more
doaj   +1 more source

Pharmaceuticals in the aquatic environment: β-blockers as a case study

, 2008
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 20/09/2008.The presence of many human pharmaceuticals in the aquatic environment is now a worldwide concern and yet little is known of the chronic effects ...
Giltrow, Emma
core  

Gravin orchestrates protein kinase A and 2-adrenergic receptor signaling critical for synaptic plasticity and memory [PDF]

, 2012
A kinase-anchoring proteins (AKAPs) organize compartmentalized pools of protein kinase A (PKA) to enable localized signaling events within neurons. However, it is unclear which of the many expressed AKAPs in neurons target PKA to signaling complexes ...
Huang, T., Day, Jonathan P., Day, Jonathan P, Baillie, George S., Guercio, L.A., Luczak, V., Nie, T., Scott, J.D., Guercio, Leonardo A., Baillie, G.S., Abel, T., Gelman, I.H., Park, Alan J, Canton, David A., Scott, John D., Havekes, R., Nie, Ting, Gelman, Irwin H, Canton, D.A., Park, Alan J., Grimes, Quinn, Grimes, Q., Luczak, Vincent G, Havekes, Robbert, Park, A.J., Guercio, Leonardo A, Baillie, George S, Abel, Ted, Gelman, Irwin H., Luczak, Vincent, Day, J.P., Canton, David A, Huang, Ted   +32 more
core   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Betabloqueador tópico pode determinar resultados inconclusivos no ecocardiograma sob estresse com dobutamina em pacientes com glaucoma Topical betablocker use can result in inconclusive dobutamine stress echocardiography in patients with glaucoma

Arquivos Brasileiros de Cardiologia, 2007
O ecocardiograma sob estresse com dobutamina é um método bem estabelecido para avaliar doença arterial coronária, cuja sensibilidade tem sido potencializada pela adição de atropina no final do protocolo.
Adriana Cordovil, Fernando Q. Matos, Orlando Campos Filho, Augusto Paranhos Jr., Ana Clara T. Rodrigues, Márcia V. Albernaz, Angelo A. V. de Paola, Antonio Carlos C. Carvalho   +7 more
doaj   +1 more source

Beta-adrenergic receptors on canine coronary collateral vessels: characterization and function

, 1989
The present studies were performed to examine the role of beta-adrenergic receptors in modulating smooth muscle tone in mature coronary collaterals.
R. D. Feldman, S. T. Paul, D. G. Harrison, J. P. Christy   +3 more
core   +1 more source