Results 131 to 140 of about 19,951 (230)

Cardiac output limits maximal oxygen consumption, but what limits maximal cardiac output?

Experimental Physiology, EarlyView.
Abstract Maximal oxygen uptake/consumption is an important variable determining exercise performance. It is generally considered to be limited largely, but not exclusively, by maximal cardiac output (CO), which limits the ability of heart to pump oxygen‐rich arterial blood to working muscles. Cardiac output is a product of heart rate and stroke volume,
Ilkka Heinonen
wiley   +1 more source

Mechanisms mediating muscle metaboreflex control of cardiac output during exercise: Impaired regulation in heart failure

Experimental Physiology, EarlyView.
Abstract The ability to increase cardiac output during dynamic exercise is paramount for the ability to maintain workload performance. Reflex control of the cardiovascular system during exercise is complex and multifaceted involving multiple feedforward and feedback systems.
Donal S. O'Leary, Joseph Mannozzi
wiley   +1 more source

[Adrenergic beta-antagonists: treatment of heart failure].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1997
M, Yokoyama, Y, Yokota
openaire   +1 more source

Beta-adrenergic receptor blockers improve survival in patients with advanced non-small cell lung cancer combined with hypertension undergoing radiotherapy. [PDF]

Sci Rep
Liang X, Li P, Qin Y, Mo Y, Chen D.
europepmc   +1 more source

Brown and beige adipose tissue‐derived metabokine and lipokine inter‐organ signalling in health and disease

Experimental Physiology, EarlyView.
Abstract Adipose tissue has an established endocrine function through the secretion of adipokines. However, a role for bioactive metabolites and lipids, termed metabokines and lipokines, is emerging in adipose tissue‐mediated autocrine, paracrine and endocrine signalling and inter‐organ communication. Traditionally seen as passive entities, metabolites
Anna Malicka, Aysha Ali, Amanda D. V. MacCannell, Lee D. Roberts   +3 more
wiley   +1 more source

Association between beta-1-adrenoceptor blockade and risk of Raynaud's phenomenon: Mendelian randomisation study. [PDF]

J Scleroderma Relat Disord
Williams JC, Rogers K, Coulson K, Hughes DM, Hughes M, Zhao SS.   +5 more
europepmc   +1 more source

Impact of exercise training on tumour‐infiltrating T cells in human prostate cancer: A secondary analysis of a randomized controlled trial (PRO‐TEST)

Experimental Physiology, EarlyView.
Abstract Exercise training reduces tumour growth by increasing tumour‐infiltrating T‐cell density in preclinical models. However, it remains unknown whether exercise training can modify intratumoural T cells in humans.The aim of this study was to compare the effects of an exercise training intervention versus control on human prostate intratumoural T ...
Simon Nørskov Thomsen, Emil Wriedt, Marianne Gardar Stærk, Sissal Sigmundsdottir Djurhuus, Birgitte Grønkær Toft, Sabrina Wielsøe, Andreas Røder, Thomas Hasselager, Peter Busch Østergren, Henrik Jakobsen, Klaus Brasso, Jesper Frank Christensen, Louise Lang Lehrskov, Casper Simonsen   +13 more
wiley   +1 more source

Oral cancer cells secrete stress neurotransmitter and proliferate in response to tobacco carcinogen NNK. [PDF]

Endocr Oncol
Verza FA, Santos-Sousa AL, Oliveira SHP, Bernabé DG.   +3 more
europepmc   +1 more source

Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders

The Journal of Physiology, EarlyView.
Abstract figure legend The carotid body develops aberrant high activity in chronic heart failure, resistant hypertension, obstructive sleep apnoea (OSA) and diabetes. Hyperactivity of the carotid body leads to both high tonicity and increased sensitivity of the arterial chemoreflex with resultant sympathoexcitation.
Tymoteusz Żera, Bartłomiej Paleczny, Maciej Siński, Sílvia V. Conde, Krzysztof Narkiewicz, Piotr Ponikowski, Julian F.R. Paton, Piotr Niewiński   +7 more
wiley   +1 more source

Acute mental stress-induced alpha or beta-adrenergic reactivity patterns linked to unique cardiometabolic risk profiles. [PDF]

Sci Rep
Wentzel A, Naudé D, von Känel R.
europepmc   +1 more source