Results 131 to 140 of about 111,593 (328)

Ligand Recognition and Function of TAARs

open access: yesSensory Neuroscience, EarlyView.
The trace amine‐associated receptor (TAAR) family represents a highly conserved group of G protein‐coupled receptors (GPCRs) in vertebrates. TAARs specifically bind to different amine ligands and mediate a variety of physiological and behavioral processes.
Kang‐Ying Qian   +3 more
wiley   +1 more source

Lung‐Derived Small Extracellular Vesicles Containing miR‐15a‐5p/miR‐96‐5p Promote Myocardial Fibrosis in Hypertrophic Cardiomyopathy via Targeting SMAD7

open access: yesSmall, EarlyView.
Small extracellular vesicles (sEVs) are critical regulators of inter‐tissue communication in cardiovascular diseases. In this study, it is found that lung‐derived sEVs enhance cardiac fibroblasts activation and aggravates myocardial fibrosis progression in hypertrophic cardiomyopathy (HCM). sEVmiR‐15a‐5p and sEVmiR‐96‐5p exert this effect via targeting
Minwen Long   +10 more
wiley   +1 more source

Decatecholaminization and calcium sensitizers in critically ill patients

open access: yesResearch in Cardiovascular Medicine, 2014
Samad E J Golzari, Ata Mahmoodpoor
doaj   +1 more source

Efficacy of Newly Synthesized 44Bu Ultrashort-Acting Beta-Adrenergic Antagonist to Isoprenaline-Induced Tachycardia – Comparison With Esmolol [PDF]

open access: hybrid, 2004
Ladislava Bartošová   +8 more
openalex   +1 more source

Emerging Nanonutraceuticals against Obesity

open access: yesSmall Science, EarlyView.
This overview comprehensively compiles the latest research advancements in diversiform nanonutraceuticals against obesity. These nanonutraceuticals are derived from the nanomodifications of some carbohydrates, lipids, proteins, vitamins, minerals, and phytochemicals.
Linjie Ni   +8 more
wiley   +1 more source

Pepducin-mediated cardioprotection via β-arrestin-biased β2-adrenergic receptor-specific signaling [PDF]

open access: yes, 2018
Reperfusion as a therapeutic intervention for acute myocardial infarction-induced cardiac injury itself induces further cardiomyocyte death. β-arrestin (βarr)-biased β-adrenergic receptor (βAR) activation promotes survival signaling responses in vitro ...
Benovic, Jeffrey L.   +7 more
core   +1 more source

Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons

open access: yesSmall Science, EarlyView.
This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong   +4 more
wiley   +1 more source

Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma [PDF]

open access: hybrid, 2013
Jennifer K. Wolter   +8 more
openalex   +1 more source

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