Results 171 to 180 of about 19,951 (230)

β-blocker suppresses both tumoral sympathetic neurons and perivascular macrophages during oncolytic herpes virotherapy. [PDF]

J Immunother Cancer
Kyritsi K, Pacholczyk R, Douglass E, Yu M, Fang H, Zhou G, Kaur B, Wang Q, Munn DH, Hong B.   +9 more
europepmc   +1 more source

Viscoelastic HyA Hydrogel Promotes Recovery of Muscle Quality and Vascularization in a Murine Model of Delayed Rotator Cuff Repair

Advanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
Rotator cuff tears, a common musculotendinous injury, often lead to permanent functional disability. A novel hyaluronic acid‐based hydrogel shows promise in promoting muscle regeneration after rotator cuff repair. The hydrogel reduces fibrosis, fatty infiltration, and muscle atrophy while supporting vascularization in a murine model.
Morgan R. Pfaff, Aboubacar Wague, Michael Davies, Anouk R. Killaars, Derek Ning, Steven Garcia, Anthony Nguyen, Prashant Nuthalapati, Mengyao Liu, Xuhui Liu, Brian T. Feeley, Kevin E. Healy   +11 more
wiley   +1 more source

Heart Failure and Osteoporosis: Shared Challenges in the Aging Population. [PDF]

J Cardiovasc Dev Dis
Spoladore R, Ciampi CM, Ossola P, Sultana A, Spreafico LP, Farina A, Fragasso G.   +6 more
europepmc   +1 more source

Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning‐Based Advanced Perspectives

Advanced Science, Volume 12, Issue 15, April 17, 2025.
Graphic illustration showing the strategic approaches based on the currently investigated evidence of psychedelics that suggests the challenges and how to address the prescription of mental disorders. These applicable avenues may provide substantial insight into distinguishing between brain networks and psychedelics.
Sung‐Hyun Kim, Sumin Yang, Jeehye Jung, Jeonghyeon Choi, Mingon Kang, Jae‐Yeol Joo   +5 more
wiley   +1 more source

Baicalin Prevents Chronic β-AR Agonist-Induced Heart Failure via Preventing Oxidative Stress and Overactivation of the NADPH Oxidase NOX2. [PDF]

J Cell Mol Med
Ge Y, Ma E, Guo X, Wang Q, Zhu W, Ren DN, Wo D.   +6 more
europepmc   +1 more source

TRIM56 Promotes White Adipose Tissue Browning to Attenuate Obesity by Degrading TLE3

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This study pinpoints TRIM56 as a viable candidate for promoting white adipose tissue browning and as a promising therapeutic target for addressing obesity and metabolic disorders. Functioning as an E3 ubiquitin ligase, TRIM56 facilitates the degradation of the TLE3 protein, thereby accelerating the thermogenic process and enhancing energy expenditure ...
Haojie Qin, Yi Zhong, Jinhui Huang, Yanli Miao, Meng Du, Kai Huang   +5 more
wiley   +1 more source

Bioactive Inorganic Materials for Innervated Multi‐Tissue Regeneration

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This review comprehensively summarizes the recent advancements of inorganic biomaterials for innervated multi‐tissue regeneration. It emphasizes the design principles of inorganic‐based material composites and their application in functional regeneration of nerves, bone, muscles, skin, and cavernous tissues.
Hongjian Zhang, Ziyi Zhao, Chengtie Wu
wiley   +1 more source

Pharmacological Treatment of Ascites: Challenges and Controversies. [PDF]

Pharmaceuticals (Basel)
Lai JC, Dai J, Liang LY, Wong GL, Wong VW, Yip TC.   +5 more
europepmc   +1 more source

Hybrid Electro‐optical Stimulation Improves Ischemic Brain Damage by Augmenting the Glymphatic System

Advanced Science, Volume 12, Issue 13, April 3, 2025.
A device is developed that allows simultaneous electrical and optical stimulations. The stimulator modulates AQP4 polarization, which is essential for enhancing glymphatic clearance, thus improving brain recovery from ischemic damage and reducing neurological, motor, and cognitive deficits.
Min Jae Kim, Jiman Youn, Hong Ju Lee, Seo‐Yeon Lee, Tae‐Gyu Kim, Young‐Jin Jung, Yong‐Il Shin, Byung Tae Choi, Joonsoo Jeong, Hwa Kyoung Shin   +9 more
wiley   +1 more source

The Role of microRNA in Overactive Bladder: Relationship and Clinical Correlation. [PDF]

Medicina (Kaunas)
Küçüker K, Aybek H, Akça H, Karagür ER, Fırat E, Özlülerden Y, Çelen S, Aybek Z.   +7 more
europepmc   +1 more source