In rat adipocyte membranes, both beta-adrenergic agonists and beta-adrenergic antagonists competed with (--)[3H]dihydroalprenolol for high affinity (KD 2-4 nM) and low capacity binding sites.
E M Dax, J S Partilla, R I Gregerman
doaj +1 more source
Adrenergic systems regulate both cognitive function and immune function. The primary source of adrenergic signaling in the brain is norepinephrine (NE) neurons of the locus coeruleus (LC), which are vulnerable to age-related degeneration and are one of ...
Andrew K. Evans +5 more
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Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G +6 more
core +2 more sources
Use of an ultrashort-acting selective β1-adrenergic receptor antagonist esmolol in ear, nose and throat surgery [PDF]
Background / Aim: The concept of general balanced anaesthesia was devised in order to assure cardiovascular stability and fast post-anaesthesia recovery.
Lončar-Stojiljković Dragana +2 more
doaj +1 more source
Norepinephrine and dopamine increase motility, biofilm formation and virulence of Vibrio harveyi [PDF]
Vibrio harveyi is one of the major pathogens of aquatic organisms, affecting both vertebrates and invertebrates, and causes important losses in the aquaculture industry.
Bossier, Peter +3 more
core +2 more sources
An assay for beta-adrenergic receptors in isolated human fat cells.
The beta-adrenergic receptors have been characterized in isolated human adipocytes using a potent beta-adrenergic antagonist (-)-[3H]dihydroalprenolol.
P Engfeldt +3 more
doaj +1 more source
Esmolol as an adjunct to general balanced anaesthesia in neurosurgery [PDF]
Background/Aim: In surgery, and especially in the neurosurgical operations, maintenance of cardiovascular stability during and in the phase of the immediate postoperative recovery is of vital importance.
Lončar-Stojiljković Dragana +2 more
doaj +1 more source
Involvement of Noradrenergic Neurotransmission in the Stress- but not Cocaine-Induced Reinstatement of Extinguished Cocaine-Induced Conditioned Place Preference in Mice: Role for β-2 Adrenergic Receptors [PDF]
The responsiveness of central noradrenergic systems to stressors and cocaine poses norepinephrine as a potential common mechanism through which drug re-exposure and stressful stimuli promote relapse.
A Dzung Lê +86 more
core +3 more sources
Introduction: Locally advanced non-small cell lung cancer (NSCLC) is highly resistant to chemoradiotherapy, and many cancer patients experience chronic stress.
K. Chaudhary +9 more
semanticscholar +1 more source
Functional selectivity of GPCR-directed drug action through location bias. [PDF]
G-protein-coupled receptors (GPCRs) are increasingly recognized to operate from intracellular membranes as well as the plasma membrane. The β 2 -adrenergic GPCR can activate G s -linked cyclic AMP (G s -cAMP) signaling from endosomes.
Conti, Marco +6 more
core +3 more sources

