Results 231 to 240 of about 111,593 (328)

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

MY336-a, a novel .BETA.-adrenergic receptor antagonist produced by Streptomyces gabonae.

open access: bronze, 1986
Hiroshi Kase   +6 more
openalex   +2 more sources

The hyperaemic and metaboreflex response of the diaphragm during fatiguing diaphragmatic work in humans

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Increasing diaphragmatic work using inspiratory pressure‐threshold loading results in activation of the inspiratory muscle metaboreflex (IMM), an increase in diaphragm blood flow, and development of diaphragm fatigue. However, how IMM sensitivity and fatigue development relate to diaphragm blood flow is not well understood ...
Megan L. Lance   +8 more
wiley   +1 more source

Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT.

open access: yesHealth Technol Assess
Devereux G   +22 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani   +5 more
wiley   +1 more source

Management Strategies for Refractory Esophageal Varices

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley   +1 more source

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