Results 271 to 280 of about 111,593 (328)

Deciphering complexity of GPCR signaling and modulation: implications and perspectives for drug discovery. [PDF]

Clin Sci (Lond)
Costa-Neto CM, Parreiras-E-Silva LT.
europepmc   +1 more source

A point mutation in the seventh hydrophobic domain of the alpha 2 adrenergic receptor increases its affinity for a family of beta receptor antagonists

, 1991
S Suryanarayana, David A. Daunt, Mark von Zastrow, Brian K. Kobilka   +3 more
openalex   +1 more source

Rare but relevant: Hydrocarbons and sudden sniffing syndrome

Addiction, Volume 120, Issue 9, Page 1884-1888, September 2025.
Abstract Inhaled hydrocarbon‐associated sudden collapse (IHASC), often referred to as ‘sudden sniffing death syndrome’ is a critical and often fatal event linked to the inhalation of volatile hydrocarbons, primarily occurring in adolescents and young adults. This syndrome manifests as sudden cardiac and/or respiratory arrest, typically occurring during
Ingrid Berling, Geoffrey Kennedy Isbister   +1 more
wiley   +1 more source

Exploring the Role of Genetic and Genomic Factors in Therapeutic Response to Heart Failure: A Comprehensive Analytical Review. [PDF]

Genes (Basel)
Ferro A, Segreti A, Crispino SP, Cricco R, Di Cristo A, Ciancio M, Gurrieri F, Ussia GP, Grigioni F.   +8 more
europepmc   +1 more source

Effects of a Beta Adrenergic Antagonist Combined with Vasodilators on Cardiac Arrhythmia in Ischemic-induced Rat Hearts

, 2007
Promporn Raksaseri, Wuthichai Klomkleaw, Suwanakiet Sawangkoon   +2 more
openalex   +2 more sources

GPCR‐G protein signalling and its mutational landscape in cancer—Driver or passenger

British Journal of Pharmacology, Volume 182, Issue 17, Page 3975-3989, September 2025.
G protein‐coupled receptors (GPCRs) play a crucial role in cellular signalling, regulating various physiological processes. Abnormal expression and mutations of GPCRs have been implicated in several types of cancer, influencing tumour initiation, progression and immune response.
Chenlin Feng, Jasper F. Ooms, Erik H. J. Danen, Laura H. Heitman   +3 more
wiley   +1 more source

Monitoring Serum Bisoprolol Concentrations in Patients With Heart Failure With Reduced Ejection Fraction: Results of a Pilot Study From Routine Health Care. [PDF]

Pharmacol Res Perspect
Kacirova I, Lazarova M, Urinovska R, Dodulik J, Drienikova D, Vaclavik J.   +5 more
europepmc   +1 more source

Disrupted circadian rhythms and opioid‐mediated adverse effects: Bidirectional relationship and putative mechanisms

Journal of Neuroendocrinology, Volume 37, Issue 9, September 2025.
Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard, Maedeh Ghasemi, Ehsan Saboory   +2 more
wiley   +1 more source

Adrenergic blockers, statins, and non-steroidal anti-inflammatory drugs are associated with later age at onset in Parkinson's disease. [PDF]

J Neurol
Malatt C, Maghzi H, Hogg E, Tan E, Khatiwala I, Tagliati M.   +5 more
europepmc   +1 more source