Alpha- and beta-adrenergic mediation of changes in metabolism and Na/K exchange in rat brown fat [PDF]
, 1985 Double- and triple-barreled ion-sensitive microelectrodes were used to measure changes in extracellular K+ and Na+ concentrations ([K+]o, [Na+]o) in brown fat.
Coles, Jonathan A. +2 more
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Towards the convergent therapeutic potential of GPCRs in autism spectrum disorders [PDF]
arXiv, 2022 Changes in genetic and/or environmental factors to developing neural circuits and subsequent synaptic functions are known to be a causative underlying the varied socio-emotional behavioural patterns associated with autism spectrum disorders (ASD). Seven transmembrane G protein-coupled receptors (GPCRs) comprising the largest family of cell-surface ...
arxiv
Assessing the clinical value of fast onset and sustained duration of action of long-acting bronchodilators for COPD [PDF]
, 2015 Date of Aceptance: 12/02/2015 Acknowledgments The authors were assisted in the preparation of the manuscript by Sarah Filcek, a professional medical writer at CircleScience (Tytherington, UK), part of KnowledgePoint360, an Ashfield Company.
Beeh, Kai M +3 more
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Management of hypertension in children and adolescents [PDF]
, 2014 Hypertension has been recognized as an important health issue in the pediatric population over the past years. This emphasizes the need for an organized and effective plan for diagnosis and management. This review provides information to guide physicians
De Bruyne, Pauline, Vande Walle, Johan
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Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength [PDF]
, 2014 Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against bone
Apel +39 more
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Use of Beta-Blockers as a First-Line Treatment for Primary Hypertension
HeartsBackground: Even though beta-blockers had been used as a first-line therapy for hypertension, since the late 1960s, the Eighth Joint National Committee, JNC 8, decided to recommend them no longer.
Maryam Izadi +2 more
doaj +1 more source
Management of Hypertrophic Obstructive Cardiomyopathy with Concurrent Hypertension and Intracerebral Haemorrhage: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchHypertrophic Obstructive Cardiomyopathy (HOCM) is primarily a hereditary genetic disorder that presents difficulties in managing hypertension using a wide range of antihypertensive medications.
Sangram Mangudkar +4 more
doaj +1 more source
Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
, 2019 Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G +6 more
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Hepatic fibrogenesis requires sympathetic neurotransmitters [PDF]
, 2004 Background and aims: Hepatic stellate cells (HSC) are activated by liver injury to become proliferative fibrogenic myofibroblasts. This process may be regulated by the sympathetic nervous system (SNS) but the mechanisms involved are unclear.
Diehl, AM +11 more
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Micro-RNAS that control myosin expression and myofiber identity [PDF]
, 2015 The present invention relates to the identification of two microRNAs, miR-499 and miR-208b, that repress fast skeletal muscle contractile protein genes. Expression of miR-499 and/or miR-208b can be used to repress fast fiber genes and activate slow fiber
Olson, Eric N., van Rooij, Eva
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