Results 131 to 140 of about 136,170 (301)
Cancer pain: current practice and emerging targets
British Journal of Pharmacology, EarlyView.Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye +5 more
wiley +1 more source
Nociceptive Effects of Locally Treated Metoprolol
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2015 Purpose: Beta (beta-)-adrenergic receptor antagonists, such as metoprolol, are often used to avoid circulatory complications during anesthesia for their antihypertensive and anti-tachycardia effects in patients with cardiovascular diseases.
Nursima Cukadar +6 more
doaj
Intravenous ephedrine abolished suspected bronchoconstriction during general anesthesia in a patient undergoing beta-adrenergic blocker therapy for hypertension. [PDF]
Saudi J Anaesth, 2019 Oshika H, Koyama Y, Usuda Y, Andoh T.
europepmc +1 more source
Students Sitting in Grass Talking
, 1940 This is a black and white photo of two students, who are women, sitting in grass talking. The two students are sitting in the grass with their legs to the side, and they are both wearing dressed. One student has a binder or book in her lap.
Blocker, Fred A.
core
Cardiotoxicity of BRAF/MEK inhibitors
British Journal of Pharmacology, EarlyView.Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe +4 more
wiley +1 more source
, 1940 This is a black and white photo of baseball players sitting in a dugout. The whole team seems to be sitting in the dugout for the photo. There are bleachers behind the dugout.
Blocker, Fred A.
core
The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment
British Journal of Pharmacology, EarlyView.Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton +6 more
wiley +1 more source
Band Playing in M Formation on Scott Field
, 1940 This is a black and white photo of a band playing on a football field in the formation of an M at Scott Field. In the background, about half of the stands are shown. It is semi-filled with spectators. There are also spectators in the foreground.
Blocker, Fred A.
core
British Journal of Pharmacology, EarlyView.Background and Purpose Degeneration of the pontine noradrenergic and midbrain dopaminergic systems contributes to cognitive‐behavioural disturbances during the prodromal stages of Alzheimer's disease (AD). We developed a genetically engineered, programmable probiotic Escherichia coli Nissle 1917 strain (EcNrhaL‐DOPA) capable of producing L‐3,4 ...
Mona Abdelhamid +9 more
wiley +1 more source
, 1940 This is a black and white photo of a woman posing in the grass. The woman is wearing a sundress and two necklaces, and she is looking at the camera and smiling.
Blocker, Fred A.
core