Results 151 to 160 of about 136,170 (301)
, 1940 This is a black and white photo of three students posing for a photo at a dance. The three students, who are men, are standing with their arms around one another\u27s shoulders.
Blocker, Fred A.
core
The FEBS Journal, EarlyView.We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti +11 more
wiley +1 more source
Student Standing in front of Old Main Dormitory
, 1940 This is a black and white photo of a student standing in front of Old Main Dormitory with a folder in his hands. The man is wearing slacks, a button-up shirt, and a tie.
Blocker, Fred A.
core
Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice
The FEBS Journal, EarlyView.Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan +8 more
wiley +1 more source
, 1940 This is a black and white photo of four students relaxing by a pool. There is a pool to the left of the students, and the students are seated or laying on towels beside the pool.
Blocker, Fred A.
core
Tankyrase‐2 regulates adipocyte differentiation through AMPK/mTOR signaling
The FEBS Journal, EarlyView.Tankyrase 2 (TNKS2), a PARP family member, underpins adipocyte differentiation. TNKS2 controls LKB1 protein level, and consequently, the activity of the mTOR/AMPK system and adipocyte differentiation through a layered process. Pharmacological inhibition of TNKS2 leaves other PARPs and DNA repair active and therefore represents a novel target in ...
Boglarka Rauch +7 more
wiley +1 more source
Student Standing in front of Tree
, 1940 This is a black and white photo of a student standing in front of a tree. The student is wearing a baseball cap, and he is standing in front of a large tree. He reaches about half the height of the photo.
Blocker, Fred A.
core
Headache: The Journal of Head and Face Pain, EarlyView.Abstract Objective To present a practical, evidence‐based framework for the management of headache disorders in pediatric patients with prior stroke or underlying cerebral vascular lesions, with particular attention to safety and efficacy of pharmacologic and non‐pharmacologic therapies.
Allison C. Hyland +7 more
wiley +1 more source
, 1940 This is a black and white photo of three students, two men and one woman, sitting on a concrete railing and laughing. Another student, who is a woman, can be partially seen on the right.
Blocker, Fred A.
core
Journal of Fish Biology, EarlyView.Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams +6 more
wiley +1 more source