Results 161 to 170 of about 2,589,815 (356)

Therapeutic role of nifedipine in threatened preterm labor: Current evidence and future perspectives

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Preterm birth occurs in approximately 10% of all pregnancies, and is not only the leading cause of neonatal mortality but also a major contributor to short‐ and long‐term morbidities due to immaturity. Preterm birth has also been linked to an increased risk of maternal cardiovascular and cerebrovascular diseases, making it a critical concern ...
Hikaru Imatake, Yoshitsugu Chigusa, Haruta Mogami, Satoshi Morita, Masaki Mandai   +4 more
wiley   +1 more source

Immuno-oncological effects of the α2-adrenoceptor agonist dexmedetomidine

OncoImmunology
The α2-adrenergic receptor agonist dexmedetomidine (DEX) exerts context-dependent antitumor effects, with its efficacy influenced by dose, immune cell involvement and combination with immune checkpoint inhibitors.
Lucillia Bezu, Oliver Kepp, Guido Kroemer   +2 more
doaj   +1 more source

Molecular and pharmacological characteristics of the gerbil α1a-adrenergic receptor

, 2011
Kelly Monroe Witt, Charles S. Bockman, Herbert Dang, Daniel D. Gruber, Philine Wangemann, Margaret A. Scofield   +5 more
openalex   +2 more sources

Rabbit models of heart disease. [PDF]

, 2008
Human heart disease is a major cause of death and disability. A variety of animal models of cardiac disease have been developed to better understand the etiology, cellular and molecular mechanisms of cardiac dysfunction and novel therapeutic strategies ...
Bers, Donald M, Pogwizd, Steven M
core  

ADRENERGIC RECEPTORS IN RAT LIVER

, 1973
Yasumichi Hagino, Mitsuyoshi Nakashima
openalex   +1 more source

ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION [PDF]

, 2018
Abnormalities in cardiac stress signaling underlie a number of cardiovascular diseases (e.g. arrhythmias and heart failure). Cardiac stress signaling pathways normally integrate signals from the sympathetic nervous system to promote efficient contraction
Baldwin, Tanya A., Baldwin, Tanya A.
core   +1 more source

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

iNew Medicine, EarlyView.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

Study of the Trp64Arg polymorphism of the beta3-adrenergic receptor in Greek women with gestational diabetes. [PDF]

, 2000
Maria Alevizaki, L Thalassinou, S. I. Grigorakis, George Philippou, Kyriaki Lili, A. Souvatzoglou, E. Anastasiou   +6 more
openalex   +1 more source

GPCR Engineering Yields High-Resolution Structural Insights into β2-Adrenergic Receptor Function

Science, 2007
D. Rosenbaum, V. Cherezov, M. Hanson, S. Rasmussen, Foon Sun Thian, T. S. Kobilka, Hee-Jung Choi, X. Yao, W. Weis, R. Stevens, B. Kobilka   +10 more
semanticscholar   +1 more source

Anti‐CD47 antibody‐decorated and cisplatin‐containing mesoporous silica nanoparticles for targeted chemoimmunotherapy of colorectal cancer in a patient‐derived organoids xenograft model

Interdisciplinary Medicine, EarlyView.
Upon targeted binding to CD47‐overexpressing colorectal cancer (CRC) cells, the nanoparticles disrupt signal regulatory protein α‐CD47 signaling and allow for the restoration of innate immune response by tumor‐associated macrophages (TAMs) against CRC.
Albert Yu, Yibo Hou, Kaibin Huang, Xucan Gao, Rong Zeng, Chaowei Zhu, Chunhui Sun, Guocai Wang, Lei Ye, Shaohua Ma, Tian Meng, Bing Guo, Yubo Zhang, Xiaoyong Dai   +13 more
wiley   +1 more source