Vascular responses after alpha adrenergic receptor blockade [PDF]
, 1968 François M. Abboud, John W. Eckstein
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High-Resolution Crystal Structure of an Engineered Human β2-Adrenergic G Protein–Coupled Receptor
Science, 2007 V. Cherezov +10 more
semanticscholar +1 more source
Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial
ESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad +9 more
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Metabolism of Propranolol (‘Inderal’), a Potent, Specific β-Adrenergic Receptor Blocking Agent [PDF]
, 1967 Peter Bond
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Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells - Activation of protein kinase B by wortmannin-sensitive and -insensittve mechanisms [PDF]
, 1997 Previous studies using L6 myotubes have suggested that glycogen synthase kinase-3 (GSK-3) is phosphoryl ated and inactivated in response to insulin by protein kinase B (PKB, also known as Akt or RAG) (Cross, D, A, E., Alessi, D, R., Cohen, P ...
Denton, Richard M. +5 more
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Adrenergic Receptors Within the Cardiovascular System [PDF]
, 1963 Neil C. Moran
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A novel octopamine receptor with preferential expression in Drosophila mushroom bodies [PDF]
, 1998 Octopamine is a neuromodulator that mediates diverse physiological processes in invertebrates. In some insects, such as honeybees and fruit flies, octopamine has been shown to be a major stimulator of adenylyl cyclase and to function in associative ...
Han, K-A, Millar, NS
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Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling
Cell, 2015 A. Manglik +11 more
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ESC Heart Failure, EarlyView.Abstract Chronic kidney disease (CKD) and chronic heart failure (HF) frequently coexist and, when comorbid, are associated with poorer outcomes. These two diseases have common risk factors, such as diabetes, obesity and hypertension, and common pathophysiological connected mechanisms, including inflammation, endothelial dysfunction, neurohormonal ...
Johann Bauersachs +2 more
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Immuno-oncological effects of the α2-adrenoceptor agonist dexmedetomidine
OncoImmunologyThe α2-adrenergic receptor agonist dexmedetomidine (DEX) exerts context-dependent antitumor effects, with its efficacy influenced by dose, immune cell involvement and combination with immune checkpoint inhibitors.
Lucillia Bezu +2 more
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