Using microscopy and 3D confocal imaging on seven cadaveric eyes, we identified sympathetic nerves closely associated with β₂‐adrenergic receptor‐expressing macrophages in the human ciliary body (CB). These findings suggest a sympathetic‐macrophage neuroimmune link in the CB, potentially influencing ocular inflammation and degeneration, warranting ...
Tanya S. Karakyriakou +6 more
wiley +1 more source
Enhanced Sampling and Tailored Collective Variables Yield Reproducible Free Energy Landscapes of Beta-1 Adrenergic Receptor Activation. [PDF]
Aureli S +3 more
europepmc +1 more source
ABSTRACT Aim Guanfacine is a second line option for management of Attention Deficit Hyperactive Disorder (ADHD) and can be prescribed adjunctively with stimulants or as monotherapy. This medical record review evaluated prescribing practices, vital sign changes over time, and client outcomes. Methods This retrospective medical record review examined 171
Oluwatomi Adeola Ibilola +2 more
wiley +1 more source
The β-adrenergic receptor-SGK1 signaling pathway in brown adipocytes protects GOT1 from proteasomal degradation. [PDF]
Park CH, Park M, Collier JJ, Chang JS.
europepmc +1 more source
Management of Paediatric Acute Asthma in a Metropolitan Emergency Department: A Retrospective Audit
ABSTRACT Aim To evaluate adherence to the Sydney Children's Hospital Network (SCHN) Asthma‐Acute Management Practice Guideline in the management of paediatric patients presenting to a metropolitan emergency department (ED). Methods A cross‐sectional retrospective audit of 153 paediatric ED presentations with acute asthma between March 2023 and February
Yasmine Toufaili, Nounu Sarukkali
wiley +1 more source
Targeting β2-adrenergic receptor reduces UV-induced cutaneous damage and inflammation in a murine model. [PDF]
Shahid A +4 more
europepmc +1 more source
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth +5 more
wiley +1 more source
Repeated restraint stress-induced increase in post-surgical somatosensory hypersensitivity and affective responding is mediated by β-adrenergic receptor activation and spinal NLRP3-IL1β signalling in male rats. [PDF]
Bella A +9 more
europepmc +1 more source
Myxomatous mitral valve disease, an acquired valvular degeneration, is the most common cardiac disorder in dogs, affecting approximately 10% of dogs in primary care veterinary practice. Dogs with myxomatous mitral valve disease frequently require anaesthesia for routine procedures.
I. Levinzon +3 more
wiley +1 more source

