Results 201 to 210 of about 2,542,862 (407)

Rat adipocyte β‐adrenergic receptors: evidence in favour of the heterogeneity of agonist‐binding sites and against negatively cooperative interactions [PDF]

, 1979
Yves Giudicelli, Brigitte Agli, Danièle Lacasa   +2 more
openalex   +1 more source

Association of obesity and body mass index classification with glycemic control in adults who are critically ill receiving parenteral nutrition: A retrospective study

Nutrition in Clinical Practice, EarlyView.
Abstract Background Hyperglycemia is a complication of parenteral nutrition (PN), which can be exacerbated in patients with obesity. Limited data exist on glycemic control in this population. This study aims to evaluate the association of obesity and body mass index (BMI) classification with glycemic control in patients who are critically ill initiated
Erika L. Mackie, Melissa Dang, Kimberly Sharpe, Justin Delic, James M. Hollands, Song Oh, Stacy Pasciolla, Laura Pontiggia, Diana Solomon, Angela Bingham   +9 more
wiley   +1 more source

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

Journal of Biological Chemistry, 1980
A. De Lean, J. Stadel, Robert J Lefkowitzl   +2 more
semanticscholar   +1 more source

Spatial transcriptomics exploration of the primary neuroblastoma microenvironment in archived FFPE samples unveils novel paracrine interactions

The Journal of Pathology, EarlyView.
Abstract High‐risk neuroblastomas exhibit a high degree of intratumoral heterogeneity. Single‐cell RNA sequencing has greatly improved our understanding of these tumors, but the method lacks cellular tissue context and spatial information about local signaling dynamics.
Joachim T Siaw, Peter Merseburger, Marcus Borenäs, Caroline Jansson, Jenny Karlsson, Arne Claeys, Eva Jennische, Dan E Lind, David Gisselsson Nord, Ruth H Palmer, Jimmy Van den Eynden   +10 more
wiley   +1 more source

A small molecule enhances arrestin-3 binding to the β₂-adrenergic receptor. [PDF]

Commun Chem
Kurt H, Akyol A, Son CD, Zheng C, Gado I, Meli M, Ferrandi EE, Bassanini I, Vasile F, Gurevich VV, Nebol A, Cagavi E, Morra G, Sensoy O.   +13 more
europepmc   +1 more source

Supersensitivity and Subsensitivity of the β-Adrenergic Receptor in Pineal Gland Regulated by Catecholamine Transmitter [PDF]

, 1973
Takeo Deguchi, Julius Axelrod
openalex   +1 more source

The Antidepressant Desipramine and α2-Adrenergic Receptor Activation Promote Breast Tumor Progression in Association with Altered Collagen Structure

Cancer Prevention Research, 2013
M. Szpunar, K. Burke, R. Dawes, E. Brown, K. Madden   +4 more
semanticscholar   +1 more source

Ligand Recognition and Function of TAARs

Sensory Neuroscience, EarlyView.
The trace amine‐associated receptor (TAAR) family represents a highly conserved group of G protein‐coupled receptors (GPCRs) in vertebrates. TAARs specifically bind to different amine ligands and mediate a variety of physiological and behavioral processes.
Kang‐Ying Qian, Yue Hao, Zheng Wang, Qian Li   +3 more
wiley   +1 more source

Enhanced Sampling and Tailored Collective Variables Yield Reproducible Free Energy Landscapes of Beta-1 Adrenergic Receptor Activation. [PDF]

J Chem Theory Comput
Aureli S, Rizzi V, Piasentin N, Gervasio FL.   +3 more
europepmc   +1 more source

Lung‐Derived Small Extracellular Vesicles Containing miR‐15a‐5p/miR‐96‐5p Promote Myocardial Fibrosis in Hypertrophic Cardiomyopathy via Targeting SMAD7

Small, EarlyView.
Small extracellular vesicles (sEVs) are critical regulators of inter‐tissue communication in cardiovascular diseases. In this study, it is found that lung‐derived sEVs enhance cardiac fibroblasts activation and aggravates myocardial fibrosis progression in hypertrophic cardiomyopathy (HCM). sEVmiR‐15a‐5p and sEVmiR‐96‐5p exert this effect via targeting
Minwen Long, Jinpeng Sun, Dongli Zhou, Can Chen, Jiangcheng Shu, Xiaobo Mao, Kunwu Yu, Minglu Liang, Long Chen, Yumei Wang, Min Cheng   +10 more
wiley   +1 more source