Results 41 to 50 of about 2,542,862 (407)

Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo. [PDF]

open access: yesPLoS ONE, 2010
RATIONALE: Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors.
Patrick F Dillon   +4 more
doaj   +1 more source

A nurse-led up-titration clinic improves chronic heart failure optimization of beta-adrenergic receptor blocking therapy : a randomized controlled trial [PDF]

open access: yes, 2014
BACKGROUND: Beta-adrenergic blockade has been shown to improve left ventricular function, reduce hospital admissions and improve survival in chronic heart failure with reduced ejection fraction (HFrEF), with mortality reduction starting early after beta ...
Driscoll, Andrea   +4 more
core   +1 more source

BIOMARKER IDENTIFICATION IN BREAST CANCER: BETA-ADRENERGIC RECEPTOR SIGNALING AND PATHWAYS TO THERAPEUTIC RESPONSE

open access: yesComputational and Structural Biotechnology Journal, 2013
Recent preclinical studies have associated beta-adrenergic receptor (β-AR) signaling with breast cancer pathways such as progression and metastasis. These findings have been supported by clinical and epidemiological studies which examined the effect of ...
Liana E. Kafetzopoulou   +4 more
doaj   +1 more source

Involvement of Toll-Like Receptor 4 in Decreased Vasopressor Response Following Trauma/Hemorrhagic Shock

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Refractory vascular failure due to the inability of vascular smooth muscle to respond to vasoconstrictors such as phenylephrine is a final common pathway for severe circulatory shock of any cause, including trauma/hemorrhagic shock ...
Rafi Mazor, PhD   +5 more
doaj   +1 more source

Adrenergic Receptors

open access: yes, 2017
This chapter will review the essential properties of adrenergic receptors in the physiology of cardiac function and in the pathology of cardiovascular disease. Following a systematic overview and a classification of adrenergic receptors, we will discuss the pathophysiological role of the sympathetic nervous system in several conditions including ...
M. Ciccarelli   +4 more
openaire   +4 more sources

Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]

open access: yes, 2017
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M.   +3 more
core   +1 more source

Augmented β2-adrenergic signaling dampens the neuroinflammatory response following ischemic stroke and increases stroke size

open access: yesJournal of Neuroinflammation, 2019
Background Ischemic stroke provokes a neuroinflammatory response and simultaneously promotes release of epinephrine and norepinephrine by the sympathetic nervous system.
Kendra J. Lechtenberg   +4 more
doaj   +1 more source

β-Adrenergic agonist and antagonist regulation of autophagy in HepG2 cells, primary mouse hepatocytes, and mouse liver. [PDF]

open access: yesPLoS ONE, 2014
Autophagy recently has been shown to be involved in normal hepatic function and in pathological conditions such as non-alcoholic fatty liver disease. Adrenergic signalling also is an important regulator of hepatic metabolism and function.
Benjamin L Farah   +6 more
doaj   +1 more source

Ligands of Adrenergic Receptors: A Structural Point of View

open access: yesBiomolecules, 2021
Adrenergic receptors are G protein-coupled receptors for epinephrine and norepinephrine. They are targets of many drugs for various conditions, including treatment of hypertension, hypotension, and asthma.
Yiran Wu, Liting Zeng, Suwen Zhao
semanticscholar   +1 more source

Adrenergic Autoantibody‐Induced Postural Tachycardia Syndrome in Rabbits

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Previous studies have demonstrated that functional autoantibodies to adrenergic receptors may be involved in the pathogenesis of postural tachycardia syndrome.
Hongliang Li   +10 more
doaj   +1 more source

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