Results 181 to 190 of about 130,584 (225)
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Journal of Pharmacology and Experimental Therapeutics, 1973
The present study was carried out to determine the effect of the prostaglandin synthesis inhibitors indomethacin and eicosa-5,8,11,14-tetraynoic acid on adrenergic responses in the dog paw perfused at constant blood flow.
B. Zimmerman +3 more
semanticscholar +1 more source
The present study was carried out to determine the effect of the prostaglandin synthesis inhibitors indomethacin and eicosa-5,8,11,14-tetraynoic acid on adrenergic responses in the dog paw perfused at constant blood flow.
B. Zimmerman +3 more
semanticscholar +1 more source
Journal of Pharmacology and Experimental Therapeutics, 1970
K 4 values have been determined for desmethylimipramine (A), imipramine (B) and their primary amine derivative (C), as well as for nortriptyline (D). The kinetic plots were made over the norepinephrine range 6 x 10 -7 M to 6 x 10 -6 M.
Maxwell Ra, Eckhardt Sb, G. Hite
semanticscholar +1 more source
K 4 values have been determined for desmethylimipramine (A), imipramine (B) and their primary amine derivative (C), as well as for nortriptyline (D). The kinetic plots were made over the norepinephrine range 6 x 10 -7 M to 6 x 10 -6 M.
Maxwell Ra, Eckhardt Sb, G. Hite
semanticscholar +1 more source
Molecular Pharmacology, 1980
The bicyclic phthalane and thiophthalane compounds, Lu 3-010 and Lu 5-003, although containing a ring system which is distinct from the ring system of tricyclic antidepressants, nonetheless, are approximately equipotent with tricyclic compounds in ...
R. Maxwell +4 more
semanticscholar +1 more source
The bicyclic phthalane and thiophthalane compounds, Lu 3-010 and Lu 5-003, although containing a ring system which is distinct from the ring system of tricyclic antidepressants, nonetheless, are approximately equipotent with tricyclic compounds in ...
R. Maxwell +4 more
semanticscholar +1 more source
Journal of Pharmacology and Experimental Therapeutics, 1987
Experiments were designed to determine the effect of estrogen pretreatment on alpha adrenergic responsiveness of blood vessels of the rabbit. Rabbits were ovariectomized and, after 8 days of recovery, treated with 17 beta-estradiol (100 micrograms i.m ...
V. Gisclard, N. Flavahan, P. Vanhoutte
semanticscholar +1 more source
Experiments were designed to determine the effect of estrogen pretreatment on alpha adrenergic responsiveness of blood vessels of the rabbit. Rabbits were ovariectomized and, after 8 days of recovery, treated with 17 beta-estradiol (100 micrograms i.m ...
V. Gisclard, N. Flavahan, P. Vanhoutte
semanticscholar +1 more source
A new inhibitor of norepinephrine uptake devoid of affinity for receptors in rat brain.
Journal of Pharmacology and Experimental Therapeutics, 1982LY135252, (+/-)-N-methyl-gamma-(2-methylphenoxy) phenylpropylamine hydrochloride, is a competitive inhibitor of norepinephrine uptake in synaptosomes of rat hypothalamus. The resolved optical (-)-isomer, LY139603, is 2 and 9 times more effective than the
D. Wong +3 more
semanticscholar +1 more source
Journal of Pineal Research
Cocaine abuse has been strongly linked to blood−brain barrier (BBB) dysfunction, though the exact mechanism by which cocaine disrupts the BBB remains unclear. In this study, we found that cocaine treatment reduces the expression of glucose transporter 1 (
Jia-Yi Wei +25 more
semanticscholar +1 more source
Cocaine abuse has been strongly linked to blood−brain barrier (BBB) dysfunction, though the exact mechanism by which cocaine disrupts the BBB remains unclear. In this study, we found that cocaine treatment reduces the expression of glucose transporter 1 (
Jia-Yi Wei +25 more
semanticscholar +1 more source
Journal of Pharmacology and Experimental Therapeutics, 1971
Tritium-labeled 5-hydroxytryptamine (3H-5-HT) is selectively taken up by elements of the myenteric plexus distinguishable from adrenergic axons. This uptake has been analyzed in vitro in a dissected preparation of longitudinal muscle and myenteric plexus.
M. Gershon, R. Altman
semanticscholar +1 more source
Tritium-labeled 5-hydroxytryptamine (3H-5-HT) is selectively taken up by elements of the myenteric plexus distinguishable from adrenergic axons. This uptake has been analyzed in vitro in a dissected preparation of longitudinal muscle and myenteric plexus.
M. Gershon, R. Altman
semanticscholar +1 more source
Beta-2 Adrenergic Agonists Are Substrates and Inhibitors of Human Organic Cation Transporter 1.
Molecular Pharmaceutics, 2015J. Salomon +6 more
semanticscholar +1 more source
Fluoxetine and two other serotonin uptake inhibitors without affinity for neuronal receptors.
Biochemical Pharmacology, 1983David T. Wong +3 more
semanticscholar +1 more source
Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
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