Results 171 to 180 of about 38,715 (223)

Neural regulation of bone: from central neural circuits to peripheral innervation of the skeletal stem cell niche. [PDF]

Bone Res
Chen Z, Luo Z, Greenblatt MB, Wu Z, Xu R.   +4 more
europepmc   +1 more source

Towards Mechanism‐Informed Treatments for Mental Health

Journal of Neurochemistry, Volume 170, Issue 5, May 2026.
Neuropsychiatric disorders impose a major global health burden, and current treatments, which historically mostly targeted dopamine and serotonin dysfunctions, often provide only partial, symptomatic relief. This review highlights emerging evidence that additional neuromodulator systems, including acetylcholine, norepinephrine, and endocannabinoids ...
Iker Bengoetxea de Tena, Farhanah Nabilah Sallie, Arvie Rodriguez Abiero, Beatrice Rizzi, Leandro Gabriel Champarini, Elisa Corti, Gianluca Masella, Ariel L. Dunn, Luisa Bandeira Binder, Tyler J. Wenzel, Agustin I. Robles, Roberta G. Anversa, Cécilia Tremblay, Aliance Romain Fokoua, Randriely Merscher Sobreira de Lima, Mateus D'Ávila, Trang T. T. Truong, Jessica C. Pierce, Rui S. Rodrigues, Luis Dinamarca‐Villarroel, Felipe Borges Almeida, Aino‐Kaisa Piironen, Andrey F. L. Aguiar, Andrés M. Jaramillo, Lucas Santos, Anja de Lange, David J. Nutt, Andrew J. Lawrence   +27 more
wiley   +1 more source

Role of the neurotransmitter-receptor pathway in T-cell tumor immunology and cancer immunotherapy. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Fan M, Zhao X.
europepmc   +1 more source

Impact of Opioid‐Free Anesthesia Combined With Enhanced Recovery After Surgery Protocol on Postoperative Recovery Quality in Patients Undergoing Laparoscopic Total Hysterectomy

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 5, May 2026.
ABSTRACT Aim Opioid‐based anesthesia in laparoscopic hysterectomy is associated with adverse effects (e.g., postoperative nausea and vomiting [PONV], ileus, cognitive impairment) that impede recovery. This study evaluates whether opioid‐free anesthesia (OFA) combined with an Enhanced Recovery After Surgery (ERAS) protocol improves postoperative ...
Yingbing Lv, Xiao Li, Yunyun Liu, Shuxia Ren, Ruiyuan Shang, Guohua Li   +5 more
wiley   +1 more source

Pancreatic cancer: molecular pathogenesis and emerging therapeutic strategies. [PDF]

Signal Transduct Target Ther
Rozengurt E, Eibl G.
europepmc   +1 more source

Influence of low‐dose dopamine on exercise in fibrosing interstitial lung disease

Experimental Physiology, Volume 111, Issue 5, Page 2682-2695, 1 May 2026.
ABSTRACT Fibrotic interstitial lung disease (FILD) is associated with dyspnoea and exercise intolerance. In other cardiorespiratory conditions, heightened carotid body (CB) chemoreflex sensitivity is associated with reduced exercise capacity. We tested the hypothesis that CB chemoreflex inhibition would improve exercise endurance time (EET) and reduce ...
Charlotte Chen, Jui‐Lin Fan, Michael Plunkett, Thalia Babbage, John Kolbe, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

Ion channels and GPCRs as pharmacological regulators of ferroptosis and pyroptosis in metabolic diseases. [PDF]

Diabetol Metab Syndr
Nurkolis F.
europepmc   +1 more source

Alcohol and Stress Together Can Lead to Long‐Term, Dementia‐Like Deleterious Effects in the Brain

Alcohol, Clinical and Experimental Research, Volume 50, Issue 5, May 2026.
Thatiane De Oliveira Sergio, Frederic W. Hopf   +1 more
wiley   +1 more source

Magnitude and variability of blood pressure and renal vascular conductance responses to postural changes, exercise, and cold in black adults: A pilot study

Physiological Reports, Volume 14, Issue 9, May 2026.
Abstract We developed a noninvasive approach to measure vascular responses to sympathetic stimuli. We hypothesized that standing, handgrip exercise, or cold exposure would raise blood pressure (BP) and lower renal vascular conductance (RVC). BP was recorded continuously and renal arterial velocity was measured using renal Doppler ultrasound.
Mohamed H. Ibrahim, Alison J. McLure, Mary J. Jackson, Brittany Harrison, Sarah Brockley, Elizabeth C. Jones, A. Parker Ruhl, Hans C. Ackerman   +7 more
wiley   +1 more source

Resting and Exercise Lactate Dynamics in Heart Failure: Guiding Therapeutic Optimization. [PDF]

Biomedicines
Ferro A, Segreti A, Tetaj N, Ciancio M, Crispino SP, Cricco R, Fossati C, Pigozzi F, Grigioni F.   +8 more
europepmc   +1 more source