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Neurotrophic factors as double-edged swords in osteosarcoma: drivers of tumour growth and immune remodelling. [PDF]
Front ImmunolLei P, Li L.
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Treatment gaps in guideline-directed medical therapy for HFrEF in Singapore: findings from a multicentre retrospective cohort study. [PDF]
BMJ OpenSenanayake S +14 more
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Canadian Journal of Physiology and Pharmacology, 1977
The effect of neuronal-uptake inhibitors on the guanethidine-induced inhibition of responses of rabbit vas deferens to transmural stimulation was investigated. The twitch and sustained reponses were inhibited by about 70% by 1.2 × 10−5 M guanethidine.
David M Paton
exaly +3 more sources
The effect of neuronal-uptake inhibitors on the guanethidine-induced inhibition of responses of rabbit vas deferens to transmural stimulation was investigated. The twitch and sustained reponses were inhibited by about 70% by 1.2 × 10−5 M guanethidine.
David M Paton
exaly +3 more sources
Developmental Biology, 1989
Tricyclic antidepressants in combination with in vitro clonal analysis of quail neural crest cells were used to examine the role the norepinephrine uptake mechanism might play in the development of adrenergic neural crest derivatives. Norepinephrine (NE) uptake inhibitors blocked expression of the adrenergic phenotype by neural crest cells.
exaly +3 more sources
Tricyclic antidepressants in combination with in vitro clonal analysis of quail neural crest cells were used to examine the role the norepinephrine uptake mechanism might play in the development of adrenergic neural crest derivatives. Norepinephrine (NE) uptake inhibitors blocked expression of the adrenergic phenotype by neural crest cells.
exaly +3 more sources
Journal of Pharmacology and Experimental Therapeutics, 1990
The effectiveness of presynaptic receptor agonists to inhibit the electrically evoked release of [3H]monoamines from brain slices is attenuated in the presence of blockade of neuronal uptake for the serotonin (5-HT) and the norepinephrine (NE) systems.
A M Galzin, S Z Langer
exaly +3 more sources
The effectiveness of presynaptic receptor agonists to inhibit the electrically evoked release of [3H]monoamines from brain slices is attenuated in the presence of blockade of neuronal uptake for the serotonin (5-HT) and the norepinephrine (NE) systems.
A M Galzin, S Z Langer
exaly +3 more sources
Acta Physiologica Scandinavica, 1969
AbstractVarious nucleotides and metabolic inhibitors have been tested on the release, reuptake and net uptake of noradrenaline (NA) in isolated splenic nerve granules. Cytidine, inosine, and uridine triphosphate facilitated uptake of NA to a similar degree as adenosine diphosphate but less than adenosine triphosphate.
U S, von Euler, F, Lishajko
exaly +3 more sources
AbstractVarious nucleotides and metabolic inhibitors have been tested on the release, reuptake and net uptake of noradrenaline (NA) in isolated splenic nerve granules. Cytidine, inosine, and uridine triphosphate facilitated uptake of NA to a similar degree as adenosine diphosphate but less than adenosine triphosphate.
U S, von Euler, F, Lishajko
exaly +3 more sources
Napamezole, an alpha-2 adrenergic receptor antagonist and monoamine uptake inhibitor in vitro.
The Journal of Pharmacology and Experimental Therapeutics, 1990Napamezole (2-[3,4-dihydro-2-naphthalenyl)methyl]-4,5-dihydro-1H- imidazole-monohydrochloride) is a selective alpha-2 adrenergic receptor antagonist and a monoamine re-uptake inhibitor in vitro. The alpha adrenergic antagonist activity of napamezole was determined in vitro in rat brain receptor binding assay using [3H]clonidine and [3H]prazosin for ...
M H, Perrone +3 more
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Journal of Neurochemistry, 1993
Abstract: The aim of this study was to evaluate the effect of citalopram, a second generation antidepressant agent producing no β‐down‐regulation, on the receptors and second messenger systems related to noradrenergic transmission in the cerebral cortex of the rat.
I, Nalepa, J, Vetulani
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Abstract: The aim of this study was to evaluate the effect of citalopram, a second generation antidepressant agent producing no β‐down‐regulation, on the receptors and second messenger systems related to noradrenergic transmission in the cerebral cortex of the rat.
I, Nalepa, J, Vetulani
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Psychopharmacology, 1988
Fluoxetine, a novel antidepressant compound that potently and selectively inhibits serotonin uptake, was chronically administered to laboratory rats. Using in vitro receptor autoradiographic techniques, we found that the binding of [3H]-dihydroalprenolol [( 3H]-DHA) decreased significantly in frontal cortex layers.
W F, Byerley +5 more
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Fluoxetine, a novel antidepressant compound that potently and selectively inhibits serotonin uptake, was chronically administered to laboratory rats. Using in vitro receptor autoradiographic techniques, we found that the binding of [3H]-dihydroalprenolol [( 3H]-DHA) decreased significantly in frontal cortex layers.
W F, Byerley +5 more
openaire +2 more sources