Results 141 to 150 of about 17,014 (180)

Might modulation of the endocannabinoid system provide a potential dual therapeutic strategy for osteoporosis and depression?

General Psychiatry, Volume 39, Issue 4, August 2026.
Peng Wei, Pianpian Zhao, Zenghui Gu, Mengyuan Yang, David Karasik, Ching‐Lung Cheung, Houfeng Zheng   +6 more
wiley   +1 more source

Pancreatic cancer cachexia promotes cardiac dysfunction through altered adrenergic signalling in the heart

The Journal of Physiology, Volume 604, Issue 15, Page 6281-6301, 1 August 2026.
Abstract figure legend The β1‐adrenergic receptor is the predominant adrenergic subtype expressed on cardiac myocytes. Upon stimulation it activates downstream signalling pathways that increase the heart rate and cardiac output to meet metabolic demands.
Parham Diba, Peter R. Levasseur, Samuel D. Newton, Khia Min Sabrina Koh, Paige C. Arneson‐Wissink, Xinxia Zhu, Peter Pham, Heike Mendez, Luke Whitcomb, Ariana Sattler, William R Woodward, Beth A. Habecker, Daniel L. Marks, Aaron J. Grossberg   +13 more
wiley   +1 more source

Recurrent bladder paraganglioma with peritoneal dissemination: An unusual pattern of metastatic progression. Case report and literature review. [PDF]

Urol Case Rep
Oliva PG, Marrero PJ, Espino RE, Marrero Domínguez R, Expósito Remedios I, Galán RC.   +5 more
europepmc   +1 more source

CaV1.2 dynamics in native male arterial myocytes

The Journal of Physiology, Volume 604, Issue 15, Page 6302-6323, 1 August 2026.
Abstract figure legend Proposed model of microtubule‐dependent CaV1.2 reorganization in vascular disease. Schematic illustration of microtubule‐mediated delivery and stabilization of CaV1.2 channels into enlarged plasma membrane clusters in response to Ang II or hyperglycaemia, promoting cooperative gating and enhanced Ca2+ influx. Abstract L‐type CaV1.
Miguel Martin‐Aragon Baudel, Hannah Voorhees, Arsalan U. Syed, Maryann K. Ferrara, Mary Horne, Johannes W. Hell, Luis F. Santana, Rose E. Dixon, Madeline Nieves‐Cintron, Manuel F. Navedo   +9 more
wiley   +1 more source

Thiamine transporter 2 and Janus kinase 2 inhibitor, fedratinib suppresses thermogenic activation of human neck area-derived adipocytes. [PDF]

Front Endocrinol (Lausanne)
Karadsheh G, Kovács E, Alrifai R, Seo M, Győry F, Csatári-Kovács R, Csősz É, Póliska S, Fésüs L, Arianti R, Kristóf E.   +10 more
europepmc   +1 more source

Pharmacology, Medicinal Chemistry, and Therapeutic Potential of Imidazoline Receptor Ligands

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Building on the excellent review article by Dardonville and Rozas (2004), this paper summarizes the most representative ligands of imidazoline receptors (IR; I1, I2, and I3) and updates their pharmacological profiles. Although not exhaustive, it provides a solid starting point for understanding the significance of I2 IRs as promising therapeutic ...
Maria‐Eleni Kouridaki, Mercè Pallàs, Carmen Escolano   +2 more
wiley   +1 more source

Outer membrane vesicles from <i>Akkermansia muciniphila</i> antagonize chronic stress-induced colorectal cancer progression by downregulating Fetuin-A. [PDF]

Front Microbiol
Zhang X, Lu Y, Jin S, Zuo Y, Zuo H, Hao Y, Xu Q, Wang M, Li Y, Li Y.   +9 more
europepmc   +1 more source

Effect of exogenous testosterone on cardiovascular, cerebrovascular, and thromboembolic adverse events: results of three complementary research designs. [PDF]

Am J Epidemiol
Vo TT, Roy S, Ye T, Erterfaie A, Pham Nguyen TP, Flory J, Leonard CE, Small DS, Hennessy S.   +8 more
europepmc   +1 more source

Osteocytes in the Metastatic Bone Niche: Mechanistic Pathways and Therapeutic Targets. [PDF]

Pharmaceuticals (Basel)
Dabaliz A, Bakir M, Fatash L, Aldoush M, Mohammad KS.   +4 more
europepmc   +1 more source

Role of the neurotransmitter-receptor pathway in T-cell tumor immunology and cancer immunotherapy. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Fan M, Zhao X.
europepmc   +1 more source