Results 101 to 110 of about 130,771 (285)
The hypothalamic-pituitary-adrenal axis in critical illness [PDF]
, 1993 Plasma ACTH and cortisol concentrations are frequently elevated in patients in intensive care units (ICU). To examine the functional integrity of the hypothalamic-pituitary-adrenal axis during critical illness, we evaluated prospectively 53 ICU patients ...
Allolio, B. +3 more
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Critical roles of endogenous glucocorticoids for disease tolerance in malaria
, 2019 During malaria, the hypothalamic-pituitary-adrenal (HPA) axis is activated and glucocorticoid (GC) levels are increased, but their essential roles have been largely overlooked.
De Bosscher, Karolien +4 more
core +1 more source
気管支喘息患者の血清コーチゾール値について. 副腎皮質ホルモン投与および年齢との関連 [PDF]
, 1995 Serum cortisol levels were examined in 94 patients with bronchial asthma in relation to dose of glucocorticoids and age. 1. The level of serum cortisol was significantly lower in group A patients, treated with glucocorticoids (prednisolone of 5mg/day or ...
Harada, Hideo +9 more
core +1 more source
Adrenocortical carcinoma (ACC): diagnosis, prognosis, and treatment
Front. Cell Dev. Biol., 2015 Adrenocortical carticnoma (ACC) is a rare malignancy with an incidence of 0.7-2.0 cases/million habitants/year. The diagnosis of malignancy relies on careful investigations of clinical, biological, and imaging features before surgery and pathological ...
R. Libé
semanticscholar +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, Volume 20, Issue 5, Page 1299-1322, May 2026.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Adrenocortical Carcinoma Presenting with Signs of Acute Abdomen
Case Reports in Surgery, 2013 Background. Adrenocortical carcinomas represent rare malignancies. In cases of hormone-secreting tumors, the hormone in excess determines the nearly diagnostic clinical presentation.
Dimitrios Symeonidis +4 more
doaj +1 more source
Behavioural and physiological consequences of acute social defeat in growing gilts: effects of the social environment [PDF]
, 2001 Endocrine, behavioural and immunologic processes, together with body growth, were evaluated in gilts that were defeated at 10 weeks of age in resident-intruder tests.
Blokhuis, Harry J., +9 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT X‐linked adrenoleukodystrophy (X‐ALD) is a genetic peroxisome disorder linked to ABCD1 mutation, characterized by rapid and complex clinical symptoms. We here report a case of X‐ALD manifesting solely as dysarthria, associated with an undefined mutation in the ABCD1 gene, underscoring the necessity of atypical clinical symptoms in X‐ALD ...
Fu‐Qing Zhang +4 more
wiley +1 more source
PLoS ONE, 2012 The orphan nuclear receptor Steroidogenic Factor-1 (SF-1, NR5A1) is a critical regulator of development and homeostasis of the adrenal cortex and gonads.
Anna Ehrlund +5 more
doaj +1 more source
No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]
, 1933 G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P. +3 more
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