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Oncocytic adrenocortical carcinoma
Urology, 2004Oncocytic adrenocortical carcinoma is rare. To our knowledge, only 6 cases have been previously reported. We describe an additional case of oncocytic adrenocortical carcinoma. A 54-year-old man presented with a right subcostal mass. Computed tomography demonstrated a massive tumor in the right abdomen.
Kazushi, Tanaka +7 more
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Pediatric adrenocortical tumours
Best Practice & Research Clinical Endocrinology & Metabolism, 2020Childhood adrenocortical tumors (ACTs) are rare, representing ∼0.2% of all pediatric malignancies and having an incidence of 0.2-0.3 new cases per million per year in the United States, but incidences are remarkably higher in Southern Brazil. At diagnosis, most children show signs and symptoms of virilization, Cushing syndrome, or both.
Emilia Modolo, Pinto +2 more
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Molecular and Cellular Endocrinology, 2004
The human adrenal cortex is a complex endocrine organ that secretes mineralocorticoids, glucocorticoids and adrenal androgens. These steroids arise from morphologically and biochemically distinct zones of the adrenal gland. Studying secretion of these distinct steroid hormones can make use of cells isolated from the adrenal gland but this requires ...
William E, Rainey +2 more
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The human adrenal cortex is a complex endocrine organ that secretes mineralocorticoids, glucocorticoids and adrenal androgens. These steroids arise from morphologically and biochemically distinct zones of the adrenal gland. Studying secretion of these distinct steroid hormones can make use of cells isolated from the adrenal gland but this requires ...
William E, Rainey +2 more
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Childhood adrenocortical tumours
European Journal of Cancer, 2004Childhood adrenocortical tumours (ACT) constitute only about 0.2% of all paediatric malignancies. However, the incidence of ACT varies across geographic regions and is remarkably high in southern Brazil. At presentation, most children show signs and symptoms of virilisation, which may be accompanied by manifestations of the hypersecretion of other ...
R C, Ribeiro, B, Figueiredo
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Endocrinology and Metabolism Clinics of North America, 2015
Recent developments in the treatment of adrenocortical carcinoma (ACC) include diagnostic and prognostic risk stratification algorithms, increasing evidence of the impact of historical therapies on overall survival, and emerging targets from integrated epigenomic and genomic analyses.
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Recent developments in the treatment of adrenocortical carcinoma (ACC) include diagnostic and prognostic risk stratification algorithms, increasing evidence of the impact of historical therapies on overall survival, and emerging targets from integrated epigenomic and genomic analyses.
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Large Adrenocortical Carcinoma
Journal of the National Medical Association, 2009Adrenal cortical carcinomas (ACCs) are rare, highly malignant tumors that carry a poor prognosis. The large size and possibility of adherence to adjacent structures can make these tumors difficult to excise. We present a patient who underwent successful resection of a massive 19-cm, nonfunctional ACC, which encased the right kidney.
Kristian L, Brown, Daniel, Bacal
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Clinics in Endocrinology and Metabolism, 1985
Adrenocortical insufficiency causes difficulty in diagnosis and morbidity out of proportion to its rarity, because of the non-specific, multi-system nature of the clinical features. Most of these are due to cortisol deficiency. Prominent features are well-known ones such as weight loss and asthenia, and hypoglycaemia.
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Adrenocortical insufficiency causes difficulty in diagnosis and morbidity out of proportion to its rarity, because of the non-specific, multi-system nature of the clinical features. Most of these are due to cortisol deficiency. Prominent features are well-known ones such as weight loss and asthenia, and hypoglycaemia.
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Surgical Clinics of North America, 2014
Although preoperative clinical, biochemical, and radiologic features can aid in the diagnosis of adrenocortical cancer (ACC), uncertainty often remains. This diagnostic ambiguity and the subsequent potential for an inadequate surgical resection have likely contributed to the currently dismal disease-free survival, although unsettlingly high rates of ...
Ryaz, Chagpar +2 more
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Although preoperative clinical, biochemical, and radiologic features can aid in the diagnosis of adrenocortical cancer (ACC), uncertainty often remains. This diagnostic ambiguity and the subsequent potential for an inadequate surgical resection have likely contributed to the currently dismal disease-free survival, although unsettlingly high rates of ...
Ryaz, Chagpar +2 more
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Molecular adrenocortical tumourigenesis
European Journal of Clinical Investigation, 2000Adrenocortical neoplasms are the most frequent abnormality of the adrenal cortex. Most of these lesions are clinically silent and are detected incidentally by ultrasound or computed tomography. The prevalence of these so‐called ‘incidentalomas’ in the general population is around 1%, increasing with age and reaching 6% among those in the age range 60 ...
M, Reincke +3 more
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Oncocytic adrenocortical carcinoma
Annals of Diagnostic Pathology, 2010Only 17 cases of oncocytic adrenocortical carcinoma have been reported in the English literature. Here, we report an incidental case of oncocytic adrenocortical carcinoma. The patient was a 69-year-old man with the chief complaint of abdominal pain. Abdominal computed tomography revealed a left adrenal tumor. No hormonal symptoms were observed.
Hiroya, Ohtake +6 more
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