Results 91 to 100 of about 13,033 (245)

Prevalence of MUTYH Monoallelic Variants in Patients With Hereditary Cancer Using Multigene Panel Testing

open access: yesCancer Medicine, Volume 14, Issue 19, October 2025.
ABSTRACT Background The MUTYH gene is involved in DNA repair and is known for MAP (MUTYH‐associated polyposis), an autosomal recessive disorder that predisposes individuals to colorectal cancer (CRC), with a lifetime risk ranging from 40% to 90%. Homozygosity or double heterozygosity (DH) for pathogenic variants (PVs) in MUTYH causes MAP, but several ...
Gemma Caliendo   +9 more
wiley   +1 more source

A Case of Unilateral Adrenal Tuberculosis in an Ethiopian Patient Presenting as a Tumor: A Diagnostic Challenge in a Resource‐Limited Setup

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Tuberculosis remains a major public health burden in developing countries, with adrenal involvement being rare and typically bilateral. Isolated adrenal tuberculosis accounts for 1%–2% of adrenal masses and often presents with nonspecific symptoms. Its imaging findings can mimic primary adrenal tumors.
Kidan Fssaha Tsehaye   +4 more
wiley   +1 more source

Significance of Dicer1 in Adrenocortical Adenoma and Carcinoma (Immunohistochemical Study) [PDF]

open access: bronze, 2023
Heba M. Rashad   +3 more
openalex   +1 more source

Bilateral Adrenal Mass Secondary to Bilateral Infantile Neuroblastoma in an Infant With Beckwith‐Wiedemann Syndrome

open access: yesClinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT Infants with Beckwith‐Wiedemann syndrome face a high risk of embryonal tumors, necessitating early and consistent surveillance. This case illustrates how timely imaging and biochemical monitoring enabled successful non‐surgical management of bilateral adrenal neuroblastoma.
Mulualeme Nigusie   +6 more
wiley   +1 more source

Effects of loperamide on the human hypothalamo-pituitary-adrenal axis in vivo and in vitro. [PDF]

open access: yes, 1992
Loperamide, an opiate agonist of high specificity for p-receptors, was recently reported to suppress ACTH and cortisol levels in normal subjects, but not in patients with proven ACTH-dependent Cushing’s disease. However, there is little information on
Auernhammer, Christoph J.   +4 more
core   +1 more source

Synchronous aldosterone- and cortisol-producing adrenocortical adenomas diagnosed using CYP11B immunohistochemistry

open access: yesSAGE Open Medical Case Reports, 2019
Immunohistochemistry with antibodies targeting enzymes responsible for the final conversion steps of cortisol (CYP11B1) and aldosterone (CYP11B2) is gaining ground as an adjunct tool in the postoperative evaluation of adrenocortical nodules.
Adam Stenman   +4 more
doaj   +1 more source

G Protein‐Coupled Receptor Signaling: Implications and Therapeutic Development Advances in Cancers

open access: yesMedComm, Volume 6, Issue 10, October 2025.
G protein‐coupled receptors (GPCRs) are the dynamic protein family in the human genome. GPCR dysregulation aids in the advancement of cancer through increased migration, survival, and proliferation. Novel treatments that target GPCR signaling include orthosteric ligands, biased receptor mutants, PROTACs, and antibody–drug conjugates.
Inamu Rashid Khan   +6 more
wiley   +1 more source

A Hybrid Machine Learning-Based Method for Classifying the Cushing's Syndrome With Comorbid Adrenocortical Lesions [PDF]

open access: yes, 2011
Background: The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. It follows from a comprehensive statistical analysis that a number of antigens such as hTERT, PCNA and Ki-67
Deng, Youping   +6 more
core   +1 more source

A glukokortikoid receptor izoformák szerepe a mellékvesekéreg daganatok patogenesisében = Role of the glucocorticoid receptor isoforms in the pathogenesis of adrenocortical tumors [PDF]

open access: yes, 2011
1-es célkitűzés: Az N363S gyakoribb míg az A3669G ritkább előfordulási gyakoriságát igazoltuk hormonálisan inaktív mellékvese adenómás betegekben a kontroll populációhoz képest. Ez az összefüggés még erősebb volt kétoldali adenómásokban.
Patócs, Attila, Zalatnai, Attila
core  

Diabetes mellitus remission in a cat with pituitary-dependent hyperadrenocorticism after trilostane treatment [PDF]

open access: yes, 2018
An 8-year-old male neutered Persian cat was presented with polyuria, polydipsia, polyphagia and muscle weakness associated with a 7 month history of diabetes mellitus (DM).
Adriana Cunha Muschner   +4 more
core   +3 more sources

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