Results 21 to 30 of about 1,396,034 (289)

Cancer Stemness Associated With Prognosis and the Efficacy of Immunotherapy in Adrenocortical Carcinoma

open access: yesFrontiers in Oncology, 2021
Background Cancer stem cells (CSCs) have been proven to influence drug resistance, recurrence, and metastasis in tumors. Our study aimed to identify stemness-related prognostic biomarkers for new therapeutic strategies in adrenocortical carcinoma ...
Xiaoxi Shi   +7 more
semanticscholar   +1 more source

Generation and characterization of a mitotane-resistant adrenocortical cell line [PDF]

open access: yes, 2020
Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy.
Bachmann, Sebastian   +14 more
core   +2 more sources

Management of adrenocortical carcinoma: are we making progress?

open access: yesTherapeutic Advances in Medical Oncology, 2021
Adrenocortical carcinoma (ACC) is a rare malignancy characterized by aggressive biology and potential endocrine activity. Surgery can offer cure for localized disease but more than half of patients relapse and primary unresectable or metastasized disease
B. Kiesewetter   +6 more
semanticscholar   +1 more source

The diagnosis and treatment of adrenocortical carcinoma in pregnancy: a case report

open access: yesBMC Pregnancy and Childbirth, 2020
Background Pregnancy complicated with adrenocortical carcinoma (ACC) is a sporadic syndrome that is characterized by hypertension, uncontrolled hypokalemia, severe heart failure, premature delivery and other adverse effects.
Yuanli Zhang   +5 more
doaj   +1 more source

Surgical Management of Adrenocortical Carcinoma: Current Highlights

open access: yesBiomedicines, 2021
Introduction: Adrenocortical carcinoma (ACC) is a rare tumor, often discovered at an advanced stage and associated with poor prognosis. Treatment is guided by staging according to the European Network for the Study of Adrenal Tumors (ENSAT ...
G. Cavallaro   +9 more
semanticscholar   +1 more source

Extra-adrenal, non-functional adrenocortical carcinoma presenting with acute abdomen: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Adrenocortical carcinoma is a rare malignancy, with 43% being non-functional. These may arise from adrenal rest anywhere in the embryonic pathway of the adrenal glands.
Alireza Mirsharifi   +4 more
doaj   +1 more source

A case of estrogen‐secreting adrenocortical carcinoma: Comprehensive immunohistochemical analysis of disorganized steroid genesis

open access: yesIJU Case Reports, 2021
Introduction Adrenocortical carcinoma rarely secretes estrogens, and little is known regarding the mechanism of intra‐tumor estrogen production. We report an estrogen‐secreting adrenocortical carcinoma in a postmenopausal woman, where comprehensive ...
Megumi Yokoyama   +8 more
doaj   +1 more source

Estrogen-secreting adrenocortical carcinoma [PDF]

open access: yesYeungnam University Journal of Medicine, 2019
Adrenocortical carcinoma is a rare type of endocrine malignancy with an annual incidence of approximately 1–2 cases per million. The majority of these tumors secrete cortisol, and a few secrete aldosterone or androgen.
You Jeong   +6 more
doaj   +1 more source

Prominent 18F-FDG Uptake in the Adrenal Gland after Contralateral Adrenalectomy in a Known Case of Adrenocortical Oncocytic Carcinoma [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2023
Adrenocortical carcinoma (ACC) is a rare type of cancer that is associated with a high rate of recurrence and poor prognosis. The main diagnostic approaches to adrenocortical cancer include CT scan, MRI and the promising role of 18F-FDG PET/CT.
Rakan Al-Rashdan   +3 more
doaj   +1 more source

Pitfalls and progress in adrenocortical carcinoma diagnosis: the utility of a multidisciplinary approach, immunohistochemistry and genomics

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2022
Adrenocortical carcinoma is a rare disease with poor prognosis whose clinical heterogeneity can at times present a challenge to accurate and timely diagnosis.
Ray Wang   +7 more
doaj   +1 more source

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