Results 61 to 70 of about 1,396,034 (289)
Aspectos clínicos e moleculares de tumor adrenocortical metacrônico pediátrico [PDF]
, 2011 The occurrence of metachronous adrenocortical carcinoma has rarely been described. We report a case of a child with virilizing adrenocortical metachronous tumors that, despite several metastases, presented long-term survival (15 years).
ALENCAR, Guilherme Asmar +8 more
core +2 more sources
Medical Approaches in Adrenocortical Carcinoma
Biomedicines, 2020 Adrenocortical carcinoma (ACC) represents one of the most aggressive endocrine tumors. In spite of a correct therapeutic strategy based on a multidisciplinary approach between endocrinologist, surgeon and oncologist, the prognosis is often poor.
R. Paragliola +5 more
semanticscholar +1 more source
Adrenocortical carcinoma [PDF]
, 2020 This thesis focuses on research of cancer of the outer layer, the cortex, of the adrenal gland: the adrenal cortex carcinoma. Adrenal cortex carcinoma is a rare form of cancer with poor prognosis. Up to 30% of patients with adrenal cortex cancer present with incurable metastatic disease, stage IV cancer.
openaire +2 more sources
Adrenocortical carcinoma: a literature review
Translational Cancer Research, 2020 Adrenocortical carcinoma (ACC) is reported to be present in 3–10% of the population with most tumors presenting as benign tumors. Most cases of ACC are a sporadic accumulation of mutations over time.
Ammu G. Thampi +3 more
semanticscholar +1 more source
The role of peroxiredoxins in cancer [PDF]
, 2017 Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO +4 more
core +1 more source
Nivolumab in metastatic adrenocortical carcinoma: results of a phase II trial.
Journal of Clinical Endocrinology and Metabolism, 2019 CONTEXT Systemic treatment of metastatic adrenocortical carcinoma (ACC) remains limited to chemotherapy and mitotane. Preliminary evidence suggesting that anti-tumor immune responses can be elicited in ACC have fostered interest in checkpoint inhibitors ...
B. Carneiro +12 more
semanticscholar +1 more source
Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice
Oncogene, 2020 Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with limited therapeutic options. The lack of mouse models that recapitulate the genetics of ACC has hampered progress in the field. We analyzed The Cancer Genome Atlas (TCGA) dataset for
K. Borges +8 more
semanticscholar +1 more source
Adrenocortical Carcinoma Presenting with Signs of Acute Abdomen
Case Reports in Surgery, 2013 Background. Adrenocortical carcinomas represent rare malignancies. In cases of hormone-secreting tumors, the hormone in excess determines the nearly diagnostic clinical presentation.
Dimitrios Symeonidis +4 more
doaj +1 more source
Scientific Reports, 2021 Adrenocortical carcinoma is a rare aggressive disease commonly recurring regardless of radical surgery. Although data on genomic alterations in malignant tumors are accumulating, knowledge of molecular events of importance for initiation of ...
Su-Chen Li +5 more
doaj +1 more source
GLUT1 expression in pediatric adrenocortical tumors: a promising candidate to predict clinical behavior [PDF]
, 2017 Background: Discrimination between benign and malignant tumors is a challenging process in pediatric adrenocortical tumors. New insights in the metabolic profile of pediatric adrenocortical tumors may contribute to this distinction, predict prognosis, as
Allolio +60 more
core +2 more sources