Results 81 to 90 of about 1,396,034 (289)

Rapidly growing adrenal gland tumor in a female patient with a history of colon cancer [PDF]

Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"
Adrenocortical carcinoma is a rare malignant disease, occurring in 0.5-2 per 1,000,000 cases annually. Clinical signs may arise due to autonomous hormonal hypersecretion by the tumor, but also due to local compressive symptoms in the abdomen. The success
Marković Bojan, Stojković Mirjana, Klet Sanja, Janić Tamara, Babić Jovana, Đurković Ivana, Nedeljković-Beleslin Biljana, Ćirić Jasmina, Žarković Miloš   +8 more
doaj   +1 more source

Hypertriglyceridemia and its impact on mitotane monitoring in adrenocortical carcinoma

Endocrinology, Diabetes & Metabolism Case Reports, 2023
Mitotane is used for treatment of advanced adrenocortical carcinoma. It is administered when the carcinoma is unresectable, metastasized, or at high-risk of recurrence after resection.
Sandra Martens, Bruno Lapauw
doaj   +1 more source

P53 mutations in human adrenocortical neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms have not been elucidated as yet. However, loss of heterozygosity at chromosomal locus 17p has been consistently observed in adrenocortical cancer.
Allolio, B., Chrousos, G. P., Karl, M., Linehan, M., Mastorakis, G., Reincke, Martin, Travis, W.   +6 more
core  

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

Open Versus Laparoscopic Adrenalectomy for Adrenocortical Carcinoma: A Meta-analysis of Surgical and Oncological Outcomes [PDF]

, 2016
PURPOSE: This study was designed to determine the role of laparoscopic adrenalectomy (LA) in the surgical management of adrenocortical carcinoma (ACC). METHODS: A systematic literature review was performed on January 2, 2015 using PubMed.
Autorino, Riccardo, Bianchi, Giampaolo, Bove, Pierluigi, Cindolo, Luca, de Sio, Marco, Fiori, Cristian, Greco, Francesco, Kim, Fernando J., Miano, Roberto, Micali, Salvatore, Nicholas, Jilian, Porpiglia, Francesco   +11 more
core   +1 more source

Genotype–Phenotype Correlations of Li–Fraumeni Syndrome in Japan Children's Cancer Group LFS20 Study Cohort

Cancer Science, EarlyView.
This study investigates genotype–phenotype correlations in Japanese families with germline TP53 pathogenic variants, collected through a nationwide prospective cancer surveillance study (JCCG LFS‐20). Among 41 families analyzed, 36 met criteria for Li–Fraumeni syndrome (LFS), and 5 were classified as attenuated LFS.
Fumito Yamazaki, Yoshiko Nakano, Masashi Sanada, Hiroki Kurahashi, Shunsuke Miyai, Arisa Ueki, Yuko Watanabe, Daisuke Hasegawa, Shuhei Karakawa, Toshifumi Ozaki, Akira Hirasawa, Akiko M. Saito, Eisuke Inoue, Motohiro Kato, Hiroyoshi Hattori   +14 more
wiley   +1 more source

Role of the mTOR pathway in normal and tumoral adrenal cells [PDF]

, 2010
The mammalian target of rapamycin (mTOR) is a kinase of the phosphoinositide 3-kinase (PI3Ks)/protein kinase B (PKB or AKT) signaling pathway, which is one of the most important intracellular mediators of the activity of growth factors receptors ...
Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Martino, M.C. (Maria Cristina) de, Pivonello, R. (Rosario)   +3 more
core   +1 more source

ARMC5-associated Bilateral Macronodular Adrenocortical Hyperplasia: A Novel Germline Variant Associated with Concomitant Papillary Thyroid Carcinoma and Meningioma [PDF]

, 2021
K. Strauss, Steven C. Smith, Amelia Grover   +2 more
openalex   +1 more source

Phase II clinical trial of pembrolizumab efficacy and safety in advanced adrenocortical carcinoma

Journal of Immunotherapy for Cancer, 2019
BackgroundAdrenocortical carcinoma (ACC) is a rare malignancy without good treatment options. There are limited data about the use of immunotherapy in ACC.
M. Habra, B. Stephen, M. Campbell, K. Hess, C. Tapia, Mingxuan Xu, J. Rodon Ahnert, C. Jimenez, Jeffrey E. Lee, N. Perrier, Russell R. Boraddus, S. Pant, V. Subbiah, D. Hong, A. Zarifa, S. Fu, D. Karp, F. Meric-Bernstam, A. Naing   +18 more
semanticscholar   +1 more source

Clinical Practice Patterns in Bone Health Assessment and Management in Endogenous Cushing's Syndrome

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Skeletal fragility is a common complication of endogenous Cushing's Syndrome (CS), although specific guidelines for managing bone health are lacking. This study aimed to assess clinicians' current engagement with bone health assessment and management in patients with endogenous CS. Design Retrospective‐cohort design. Patients Seventy‐
Preeshila Behary, Dinushan Raveendran, Ramesh Nair, Aimee Di Marco, Debbie Papadopoulou, Florian Wernig, Ali Abbara, Karim Meeran, Niamh Martin, Jeremy Cox, Alexander N. Comninos   +10 more
wiley   +1 more source