Results 11 to 20 of about 40,447 (200)

Immunohistochemical expression of CYP11A1, CYP11B, CYP17, and HSD3B2 in functional and nonfunctional canine adrenocortical tumors. [PDF]

open access: yesJ Vet Intern Med
Abstract Background Functionality of human adrenal tumors is inferred by CYP11B1 (cortisol synthase) expression, CYP11B2 (aldosterone synthase) expression, or both. Hypothesis/Objectives Nonfunctional canine adrenal tumors have low expression of steroidogenic enzymes, whereas aldosterone‐producing tumors express CYP11B, and cortisol‐producing tumors ...
Allan F, Watson AH, Syme HM.
europepmc   +2 more sources

Lived experience of people with adrenocortical carcinoma and associated adrenal insufficiency

open access: yesEndocrinology, Diabetes &Metabolism, Volume 5, Issue 4, July 2022., 2022
ACC appears to have high impact on lived experience of patients including their wellbeing and AI management. Further qualitative study is needed to understand the interactions of these two conditions, it's influences on patients' journey and survivorship.
Phillip Yeoh   +3 more
wiley   +1 more source

Cushing's syndrome caused by intra‐adrenocortical adrenocorticotropic hormone in a dog

open access: yesJournal of Veterinary Internal Medicine, Volume 36, Issue 1, Page 264-271, January/February 2022., 2022
Abstract A 13‐year‐old Labrador retriever was diagnosed with Cushing's syndrome (CS) caused by primary bilateral nodular adrenocortical hyperplasia with adrenocorticotropic hormone (ACTH) expression. The pituitary origin of CS was ruled out by suppression of plasma ACTH concentration and absence of a proliferative lesion on histological evaluation of ...
Elber A. Soler Arias   +3 more
wiley   +1 more source

Adrenal Myelolipoma Masquerading as an Adrenal Malignancy

open access: yesCase Reports in Endocrinology, Volume 2022, Issue 1, 2022., 2022
An adrenal myelolipoma presenting with suspicious features may pose a diagnostic challenge to surgeons and endocrinologists. In this case report of an adult patient with undiagnosed congenital adrenal hyperplasia presenting with bilateral adrenal masses, we review his radiographic and clinical findings which were highly suspicious for adrenal ...
Davida A. Robinson   +11 more
wiley   +1 more source

Clinical Associations of Thyroid Hormone Levels with the Risk of Atherosclerosis in Euthyroid Type 2 Diabetic Patients in Central China

open access: yesInternational Journal of Endocrinology, Volume 2020, Issue 1, 2020., 2020
Background. Thyroid function is associated with the etiology and pathogenesis of type 2 diabetes (T2D) and potentially contributes to the development of the complications of T2D. The association of thyroid hormones with atherosclerosis in euthyroid T2D patients is not clear. Purpose.
Limin Wang   +6 more
wiley   +1 more source

Microgravity versus Microgravity and Irradiation: Investigating the Change of Neuroendocrine‐Immune System and the Antagonistic Effect of Traditional Chinese Medicine Formula

open access: yesBioMed Research International, Volume 2020, Issue 1, 2020., 2020
During spaceflight, the homeostasis of the living body is threatened with cosmic environment including microgravity and irradiation. Traditional Chinese medicine could ameliorate the internal imbalance during spaceflight, but its mechanism is still unclear.
Haoru Zhu   +8 more
wiley   +1 more source

Effect of Hirsutella sinensis Fungus on the Hypothalamic‐Pituitary‐Adrenal Axis in Lewis Rats with Kidney‐Yang Deficiency Syndrome

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2020, Issue 1, 2020., 2020
Kidney‐yang deficiency syndrome (KYDS) is a classic syndrome in traditional Chinese medicine, which is mainly caused by damage to the hypothalamic‐pituitary‐adrenal (HPA) axis. Hirsutella sinensis fungus (HSF), an artificial substitute of Cordyceps sinensis, has been widely used in TCM.
Lizong Zhang   +11 more
wiley   +1 more source

Dental management of patients with endocrine disorders [PDF]

open access: yes, 2010
Introduction: The endocrine system is responsible for hormonal secretion and is closely related to the central nervous system, as it diversifies its functions through the hypothalamus and pituitary glands.
Carlos Fabuel, Laura   +2 more
core   +1 more source

Familial Micronodular Adrenocortical Disease, Cushing Syndrome, and Mutations of the Gene Encoding Phosphodiesterase 11A4 ( PDE11A) [PDF]

open access: yes, 2014
We present the pathologic findings in the adrenal glands of 4 patients, aged 10 to 38 years, with Cushing syndrome and germline inactivating mutations of the gene PDE11A4 that encodes phosphodiesterase11A4. The gene is expressed in the adrenal cortex and
Bertherat, J.   +3 more
core   +1 more source

Functional Implications of LH/hCG Receptors in Pregnancy-Induced Cushing Syndrome [PDF]

open access: yes, 2017
Context: Elevated human choriogonadotropin (hCG) may stimulate aberrantly expressed luteinizing hormone (LH)/hCG receptor (LHCGR) in adrenal glands, resulting in pregnancy-induced bilateral macronodular adrenal hyperplasia and transient Cushing syndrome (
Bertherat, Jerome   +16 more
core   +1 more source

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