Results 91 to 100 of about 1,223,943 (215)

Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development

open access: yesEnvironmental Toxicology, Volume 41, Issue 10, Page 906-921, October 2026.
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo   +10 more
wiley   +1 more source

Conventional and novel strategies in the treatment of adrenocortical cancer

open access: yesBrazilian Journal of Medical and Biological Research, 2000
Adrenocortical carcinoma is a highly malignant neoplasm with an incidence of two per million people per year. Several treatment strategies have resulted in temporary or partial tumor regression but very few cases have attained long survival.
D.E. Schteingart
doaj   +1 more source

Cushing's syndrome is associated with an advanced chronotype

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Cushing's syndrome is characterised by chronic glucocorticoid excess that abolishes the physiological circadian cortisol rhythm. We investigated whether this circadian disruption alters chronotype. In a single‐centre case–control study, chronotype was assessed using the Munich ChronoType Questionnaire (MCTQ; n = 119) and wrist actigraphy (n ...
Hanna Nowotny   +7 more
wiley   +1 more source

Genotype analysis of the human endostatin variant p.D104N in benign and malignant adrenocortical tumors

open access: yesClinics, 2012
OBJECTIVE: Endostatin is a potent endogenous inhibitor of angiogenesis. It is derived from the proteolytic cleavage of collagen XVIII, which is encoded by the COL18A1 gene. A polymorphic COL18A1 allele encoding the functional polymorphism p.D104N impairs
Beatriz Marinho de Paula Mariani   +5 more
doaj   +1 more source

Animal models of adrenocortical tumorigenesis [PDF]

open access: yes, 2012
Over the past decade, research on human adrenocortical neoplasia has been dominated by gene expression profiling of tumor specimens and by analysis of genetic disorders associated with a predisposition to these tumors.
Sara Galac   +7 more
core   +1 more source

Adrenocortical Tumors* [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 1997
Ana C. Latronico, George P. Chrousos
openaire   +2 more sources

Giant nonfunctioning adrenal tumors: two case reports and review of the literature

open access: yesJournal of Medical Case Reports, 2018
Background There are an estimated 1–2 cases per million per year of adrenocortical carcinoma in the USA. It represents a rare and aggressive malignancy; it is the second most aggressive endocrine malignant disease after anaplastic thyroid carcinoma.
George Chatzoulis   +8 more
doaj   +1 more source

Diagnosis of adrenocortical tumors by reticulin algorithm

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
To apply reticulin algorithm (RA) to the diagnosis of adrenocortical tumors on adrenalectomy specimens and compare its efficacy to the modified Weiss criteria or Lin-Weiss-Bisceglia (LWB) criteria for oncocytic variant.Adrenocortical tumors (ACTs) diagnosed on resected specimens including the variants during January 2010-June 2016 were retrieved from ...
Daphne Fonseca   +7 more
openaire   +3 more sources

Inactivation of the p16 tumor suppressor gene in adrenocortical tumors [PDF]

open access: yes, 1999
The mechanisms of adrenocortical tumorigenesis are still unknown. Evidence that the majority of adrenocortical tumors are monoclonal in origin suggests that a progressive accumulation of genetic aberrations, due to activation of protooncogenes and/or ...
BOSCARO, MARCO   +8 more
core  

Rapidly growing adrenal gland tumor in a female patient with a history of colon cancer [PDF]

open access: yesMedicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"
Adrenocortical carcinoma is a rare malignant disease, occurring in 0.5-2 per 1,000,000 cases annually. Clinical signs may arise due to autonomous hormonal hypersecretion by the tumor, but also due to local compressive symptoms in the abdomen. The success
Marković Bojan   +8 more
doaj   +1 more source

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