Results 21 to 30 of about 1,223,943 (215)

Embolization in an adrenocortical carcinoma as palliative therapy [PDF]

, 1999
Background: With an annual incidence of 0.2% of new cases per 100,000 inhabitants, adrenocortical carcinoma is rare. In advanced tumor only palliative treatment modalities are practicable. Because of scarcity of the tumor, standard treatment has not been
Kühl, M., Forstpointner, Roswitha, Braunschweig, R., Schalhorn, Andreas, Lang, N., Meissner, H., H. Meißner, M. Kühl, N. Lang, A. Schalhorn, R. Forstpointner, R. Braunschweig   +11 more
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Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R [PDF]

, 2013
Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the
Lucile Lefèvre, Ragazzon, Bruno, Constanze Hantel (280561), Guillaud-Bataille, Marine, Bruno Ragazzon (140444), Launay, Pierre, Stéphane Bonnet (280565), Marthe Rizk-Rabin (280575), Marine Guillaud-Bataille (9131), Karine Perlemoine, Lefèvre, Lucile, Sébastien Gaujoux (280559), Tissier, Frédérique, Hantel, Constanze, Frédérique Tissier (140448), Lucile Lefèvre (280570), Rizk-Rabin, Marthe, Karine Perlemoine (280567), Bertherat, Jérôme, Stéphane Bonnet, Bonnet, Stéphane, Sébastien Gaujoux, Perlemoine, Karine, Jérôme Bertherat, Bruno Ragazzon, Beuschlein, Felix, Marthe Rizk-Rabin, Frédérique Tissier, Pierre Launay (280563), Jérôme Bertherat (140471), Felix Beuschlein, Marine Guillaud-Bataille, Constanze Hantel, Felix Beuschlein (158361), Gaujoux, Sébastien, Pierre Launay   +35 more
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Neuroendocrine differentiation of adrenocortical tumors [PDF]

Cancer, 1995
The syndrome of multiple endocrine neoplasia type 1 frequently involves the adrenal cortex. The relationship between the diffuse neuroendocrine system and the adrenal cortex is not clear however, particularly as the adrenal cortex is not considered to be an intrinsic part of the diffuse neuroendocrine system.The possible relationship between the ...
H R, Haak, G J, Fleuren
openaire   +2 more sources

Clonal Composition of Human Adrenocortical Neoplasms [PDF]

, 1994
The mechanisms of tumorigenesis of adrenocortical neoplasms are still not understood. Tumor formation may be the result of spontaneous transformation of adrenocortical cells by somatic mutations.
Travis, W., Beuschlein, Felix, Karl, M., Chrousos, G. P., Abdelhamid, S., Allolio, B., Jaursch-Hancke, C., Reincke, Martin   +7 more
core   +1 more source

Abdominal wall metastasis in scar after open resection of an adrenocortical carcinoma

Clinics and Practice, 2011
A 42-year-old man patient presented with progressively increasing, occasionally painful lump in the left upper and central abdomen. Investigations revealed well-defined capsulated left adrenocortical carcinoma.
Nikhil Gupta, Umesh Bansal, Neha Mahajan, Maha Singh Yadav   +3 more
doaj   +1 more source

Precocious puberty in a child: A rare cause and review of literature

Journal of Family Medicine and Primary Care, 2022
Precocious puberty (PP) in pediatric office practice is challenging as the cause varies from benign to malignant conditions. Adrenocortical tumors are rare in childhood and pseudo-precocious puberty is the most common clinical presentation in children ...
Thulasiraj Saminathan, J Dhivyalakshmi, Latha M Sneha, Leena D Joseph   +3 more
doaj   +1 more source

No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]

, 1933
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Travis, W., Karl, M., Chrousos, G. P., Reincke, Martin   +3 more
core   +1 more source

Genetics and epigenetics of adrenocortical tumors [PDF]

Molecular and Cellular Endocrinology, 2014
Adrenocortical tumors are common neoplasms. Most are benign, nonfunctional and clinically irrelevant. However, adrenocortical carcinoma is a rare disease with a dismal prognosis and no effective treatment apart from surgical resection. The molecular genetics of adrenocortical tumors remain poorly understood.
Antonio M, Lerario, Andreas, Moraitis, Gary D, Hammer   +2 more
openaire   +2 more sources

Alterations of Phosphodiesterases in Adrenocortical Tumors [PDF]

Frontiers in Endocrinology, 2016
Alterations in the cyclic (c)AMP-dependent signaling pathway have been implicated in the majority of benign adrenocortical tumors (ACTs) causing Cushing syndrome (CS). Phosphodiesterases (PDEs) are enzymes that regulate cyclic nucleotide levels, including cyclic adenosine monophosphate (cAMP).
Hannah-Shmouni, Fady, Faucz, Fabio R., Stratakis, Constantine A.   +2 more
openaire   +3 more sources

9daiendo/Steroids-producing-adrenocortical-nodules: v1.0.0

, 2023
This code was used in the analysis of the article titled "Steroids-producing adrenocortical nodules: a novel two-layered structure as a precursor lesion of cortisol-producing adenoma"
9daiendo
core   +1 more source