Results 41 to 50 of about 1,223,943 (215)
Whole-exome sequencing for a rare case of aldosterone-producing adrenocortical carcinoma [PDF]
Jichu yixue yu linchuang, 2020 Objective Aldosterone-producing adrenocortical carcinoma(ACC) is an uncommon disease.In this paper, the genetic mutations of aldosterone-producing ACC are studied by whole-exome sequencing.
WANG Hui-ping, CHANG Xiao-yan, MA Xiao-sen, TONG An-li
doaj
KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer. [PDF]
PLoS ONE, 2011 BACKGROUND:KIAA0101 is a proliferating cell nuclear antigen-associated factor that is overexpressed in some human malignancies. Adrenocortical neoplasm is one of the most common human neoplasms for which the molecular causes are poorly understood ...
Meenu Jain +3 more
doaj +1 more source
Aspectos clínicos e moleculares de tumor adrenocortical metacrônico pediátrico [PDF]
, 2011 The occurrence of metachronous adrenocortical carcinoma has rarely been described. We report a case of a child with virilizing adrenocortical metachronous tumors that, despite several metastases, presented long-term survival (15 years).
LATRONICO, Ana Claudia +26 more
core +1 more source
Nonfunctional ectopic adrenocortical carcinoma in the lung: A case report and literature review
Frontiers in Oncology, 2023 BackgroundEctopic adrenocortical tissues and neoplasms are rare and usually found in the genitourinary system and abdominal cavity. The thorax is an extremely rare ectopic site.
Limin Nie +8 more
doaj +1 more source
Mouse models of adrenocortical tumors [PDF]
Molecular and Cellular Endocrinology, 2016 The molecular basis of the organogenesis, homeostasis, and tumorigenesis of the adrenal cortex has been the subject of intense study for many decades. Specifically, characterization of tumor predisposition syndromes with adrenocortical manifestations and molecular profiling of sporadic adrenocortical tumors have led to the discovery of key molecular ...
Kaitlin J, Basham +3 more
openaire +2 more sources
, 2023 Adrenocortical carcinoma (ACC) is a rare but highly aggressive cancer with limited treatment options and poor survival for patients with advanced disease. An improved understanding of the transcriptional programs engaged in ACC will help direct rational,
Mark J. Hoenerhoff +13 more
core +1 more source
Angiogenesis in the Normal Adrenal Fetal Cortex and Adrenocortical Tumors [PDF]
, 2021 Angiogenesis plays an important role in several physiological and pathological processes. Pharmacological angiogenesis modulation has been robustly demonstrated to achieve clinical benefits in several cancers.
Mariana P. Monteiro +7 more
core +1 more source
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
Gut‐microbiota‐brain Axis and post‐traumatic epilepsy
Epilepsia Open, EarlyView.Abstract There has been growing evidence that perturbations in gut‐microbiota‐brain axis (GMBA) are involved in mechanisms of chronic sequelae of traumatic brain injury (TBI). This review discusses the connection between GMBA and post‐traumatic epilepsy (PTE), the latter being a common outcome of TBI.
Andrey Mazarati
wiley +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source