Results 121 to 130 of about 20,049 (168)

FETAL AND NEWBORN ADRENOCORTICAL TUMORS

Fetal and Pediatric Pathology, 2010
Adrenocortical tumors occur less often in the fetus and newborn than later in life. The purpose of this study was to focus on the fetus and newborn in an attempt to determine the various ways these tumors differ in their biologic behavior, pathology, clinical presentation and response to therapy from those occurring in the older child and adolescent ...
Hart Isaacs
exaly   +3 more sources

Pathogenesis of benign adrenocortical tumors

Best Practice and Research in Clinical Endocrinology and Metabolism, 2010
Most adrenocortical tumors (ACT) are benign unilateral adrenocortical adenomas, often discovered incidentally. Exceptionally, ACT are bilateral. However bilateral ACT have been very helpful to progress in the pathophysiology of ACT. Although most ACT are of sporadic origin, they may also be part of syndromic and/or hereditary disorders.
Delphine Vezzosi, Jérôme Bertherat
exaly   +3 more sources

Outcome of adrenocortical tumors in children

Journal of Pediatric Surgery, 2008
This study reviews adrenocortical tumors in children to determine factors that significantly affect outcome.An institutional review board-approved retrospective review from 1976 to 2005 identified 23 patients younger than 19 years old with histologic confirmation of adrenocortical carcinoma (ACC) and adenomas.The mean age of the 23 children was 9.0 +/-
Tuan H Pham, Corey W Iqbal, Christopher R Moir   +2 more
exaly   +3 more sources

Adrenocortical tumors in children

Seminars in Pediatric Surgery, 2020
Adrenocortical neoplasms are rare in childhood. Unlike their adult counterparts, they are often hormonally active and malignant. Despite being uncommon, adrenocortical neoplasms in children have significant associated morbidity and require complete surgical resection for effective management.
Zachary J, Kastenberg, Eric R, Scaife
openaire   +2 more sources

Adrenocortical tumors in childhood

Pediatric Surgery International, 2003
Adrenocortical tumors (ACT) are rare in childhood. Determination of malignant potential is difficult. To assess the presentation, clinical behaviour, and histology of these tumors in our center, the records of nine patients with ACTs between 1989 and 2000 were analyzed. The age, sex, clinical presentation, investigations, treatment, follow-up data, and
K L, Narasimhan, R, Samujh, A, Bhansali, R K, Marwaha, S K, Chowdhary, B D, Radotra, K L N, Rao   +6 more
openaire   +2 more sources

The Genetics of Adrenocortical Tumors

Endocrinology and Metabolism Clinics of North America, 2015
Advances in genomics accelerated greatly progress in the study of the genetics adrenocortical tumors. Bilateral nodular hyperplasias causing Cushing's syndrome are frequently caused by germline alterations leading to cAMP/PKA pathway activation (micronodular) and ARMC5 inactivation (macronodular).
Stéphanie, Espiard, Jérôme, Bertherat
openaire   +2 more sources