Results 131 to 140 of about 20,049 (168)

Adrenocortical tumors in children

Journal of Pediatric Surgery, 2001
Etiopathogenesis and management of pediatric adrenocortical tumors (ACTs) is still obscure because of the limited number of cases. The aim of this study is to present a clear picture of the entire spectrum of pediatric ACTs by reviewing one of the largest noncollected pediatric series treated in a single medical center.Records of children treated for ...
A O, Ciftci, M E, Senocak, F C, Tanyel, N, Büyükpamukçu   +3 more
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Mutations in Adrenocortical Tumors

Hormone and Metabolic Research, 1998
Silent and incidentally detected adrenocortical neoplasms are the most frequent abnormality of the adrenal cortex. The prevalence of these lesions in the general population is around 1%, increases with age and reaches 6% in the seventh decade of life.
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Growth in children with adrenocortical tumors

Klinische Pädiatrie, 1991
Longitudinal growth was assessed in 10 children aged 0.8 to 11.8 years with adrenocortical tumors. All children had signs of androgen excess. In addition, 5 children had glucocorticoid excess, 1 child had estrogen excess. Multiple height recordings, expressed as height standard deviation score for chronological age, were available in 7 children.
B P, Hauffa, C, Roll, R, Mühlenberg, W, Havers   +3 more
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Virilizing Adrenocortical Tumors in Childhood

Pediatrics, 1986
To the Editor.— It was of considerable interest to read about the experience of virilizing adrenal tumors at the Childrens Memorial Hospital, Chicago,1 and the literature review is of particular value. In 1984, we published results from our study during 12 years of 12 infants with virilizing adrenal tumors without cortisol excess.
J W, Honour, D A, Price, D B, Grant
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Hyperandrogenism and Adrenocortical Tumors

2019
Androgen-secreting tumors are a rare cause of hyperandrogenism of adrenal origin. Although these tumors are identified in less than 2% of patients, the prevalence of adrenocortical carcinomas is relevant (2/3 of the cases). Those tumors are associated with simultaneous elevation of several androgens, mainly androstenedione, DHEAS, and testosterone, in ...
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Dysregulation of microRNAs in adrenocortical tumors

Molecular and Cellular Endocrinology, 2012
MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the epigenetic regulation of cellular processes. Different malignancies are often associated with the deregulation of specific sets of miRNAs. The prognosis of adrenocortical cancers (ACCs) is very poor as compared to adrenocortical adenomas (ACAs), and even within ACCs there are cases ...
Singh, Puneet, Soon, Patsy S H, Feige, Jean-Jacques, Chabre, Olivier, Zhao, Jing Ting, Cherradi, Nadia, Lalli, Enzo, Sidhu, Stan B   +7 more
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A Diagnostic Approach to Adrenocortical Tumors

Surgical Pathology Clinics, 2019
Adrenocortical tumors range from primary bilateral micronodular or macronodular forms of adrenocortical disease to conventional adrenocortical adenomas and carcinomas. Accurate classification of these neoplasms is critical given the varied pathogenesis, clinical behavior, and outcome of these different lesions.
Anjelica, Hodgson, Sara, Pakbaz, Ozgur, Mete   +2 more
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Aberrations of centrosomes in adrenocortical tumors

International Journal of Oncology, 2002
The frequent and generalized chromosomal imbalances that are characteristic of adrenocortical carcinomas suggest that incomplete chromosome segregation often takes place in these tumors. As a step towards elucidating the mechanism behind the multiple numerical chromosomal aberrations, we have evaluated a series of 14 such tumors for centrosome ...
Leyla, Roshani, Kaoru, Fujioka, Gert, Auer, Magnus, Kjellman, Svetlana, Lagercrantz, Catharina, Larsson   +5 more
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P53 and Ki67 in Adrenocortical Tumors

Endocrine Research, 2000
The p53 tumor-supressor gene has been reported as the most frequent genetic abnormality seen in human malignancies. Here we studied immunohistochemically the expression of p53 in a large series of adrenocortical tumors. The proliferative activity was assessed by the expression of Ki67.
J, Arola, K, Salmenkivi, J, Liu, A I, Kahri, P, Heikkilä   +4 more
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Dexamethasone-Suppressible Adrenocortical Tumor

New England Journal of Medicine, 1968
ONE of the most widely employed tests in clinical endocrinology is the dexamethasone suppression test. The applications of this test fall into two broad classes.
J W, Kendall, P R, Sloop
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