Results 121 to 130 of about 1,062,529 (285)

Improving the diagnosis of hyperphagia in melanocortin‐4 receptor pathway diseases

open access: yesObesity, Volume 33, Issue 7, Page 1217-1231, July 2025.
Abstract Characteristics of hyperphagia include heightened and prolonged hunger, longer time to satiation, shorter duration of satiety, severe preoccupation with food (i.e., hyperphagic drive), abnormal food‐seeking behaviors, and distress or functional impairment when food is unavailable.
M. Jennifer Abuzzahab   +8 more
wiley   +1 more source

Tools to Predict Unilateral Primary Aldosteronism and Optimise Patient Selection for Adrenal Vein Sampling: A Systematic Review

open access: yesClinical Endocrinology, Volume 103, Issue 1, Page 3-12, July 2025.
ABSTRACT Objective Primary aldosteronism (PA), the most common endocrine cause of hypertension, is evaluated using adrenal vein sampling (AVS), to determine if aldosterone excess is bilateral or unilateral. AVS is invasive and technically challenging; it would ideally be used only in those with unilateral PA who are candidates for surgical cure.
Elisabeth Ng   +4 more
wiley   +1 more source

Morning Salivary Cortisone Versus Serum Cortisol in the Overnight Dexamethasone Suppression Test (ODNST): Evaluation in a Clinical Setting

open access: yesClinical Endocrinology, Volume 103, Issue 1, Page 13-20, July 2025.
ABSTRACT Introduction Saliva hormone measurement is increasingly being applied in everyday clinical practice. In relation to salivary cortisone measurement, there is a particular advantage, with minimal chance of cross‐reaction with prescribed glucocorticoids and greater convenience.
Mathilde Mordaunt   +10 more
wiley   +1 more source

Adrenocorticotropic hormone gel for patients with non-infectious uveitis

open access: yesAmerican Journal of Ophthalmology Case Reports, 2019
Purpose: To describe the potential role of adrenocorticotropic hormone (ACTH) gel treatment in patients with chronic non-infectious uveitis. Observations: We report the clinical course of three patients with bilateral, non-infectious anterior and ...
Yael Sharon, David S. Chu
doaj  

Recurrent Pituitary Apoplexy In An Adenoma With Switching Phenotypes

open access: yesAACE Clinical Case Reports, 2020
: Objective: To describe an unusual presentation of a patient with recurrent pituitary apoplexy of an adenoma that switched phenotypes from a nonfunctioning, or silent gonadotroph adenoma (SGA), to a silent corticotroph adenoma (SCA).
Teresa V. Brown, DO   +2 more
doaj  

Pathogenic Deep Intronic PCSK1 Variant Causes Proprotein Convertase 1/3 Deficiency in a Family

open access: yesClinical Genetics, Volume 108, Issue 1, Page 102-106, July 2025.
Biallelic PCSK1 loss‐of‐function mutations cause proprotein convertase 1/3 (PC1/3) deficiency, a polyendocrinopathy; a total of 36 patients were reported. The first deep intronic PCSK1 variant, (NM_000439.5):c.1196+2681T>A, was found to segregate with the disease in a consanguineous family, and is shown together with 32 reported mutations.
Leah M. Huber   +6 more
wiley   +1 more source

Pathogenesis of Melasma Explained

open access: yesInternational Journal of Dermatology, Volume 64, Issue 7, Page 1201-1212, July 2025.
Pathophysiology of melasma. ABSTRACT This review provides an in‐depth analysis of the pathophysiology of melasma and highlights recent studies that elucidate its underlying mechanisms. Given the prevalence of melasma, a thorough understanding of its pathogenesis is critical for the development of effective treatment strategies.
Lara Ali, Firas Al Niaimi
wiley   +1 more source

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