Results 101 to 110 of about 454,704 (201)

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy

Journal of Small Animal Practice, EarlyView.
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth, S. M. DeMonaco, B. J. Conner, P. B. S. Serpa, A. R. Wilkinson   +4 more
wiley   +1 more source

Successful use of insect‐based (Hermetia illucens) diet in dogs with food‐responsive enteropathy

Journal of Small Animal Practice, EarlyView.
Objective Diet is an integral component of the management of chronic enteropathy in dogs. The role of insect‐based diets in this disease remains unknown. The objective of this study was to evaluate the impact of an insect‐based (Hermetia illucens) diet in dogs with presumed food‐responsive enteropathy.
K. Murtagh, E. Stavroulaki, M. Carvalho, E. J. O'Neill, C. T. Mooney   +4 more
wiley   +1 more source

Adrenocorticotropic hormone analogue as novel treatment regimen in ocular cicatricial pemphigoid

, 2018
Purpose: To report the clinical outcome of a patient with ocular cicatricial pemphigoid, treated with adrenocorticotropic hormone gel. Observations: A 75-year-old female with a biopsy proven ocular cicatricial pemphigoid (OCP) presented with bilateral ...
Yael Sharon, David S. Chu
core   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Transcriptome-Wide Analysis of Pituitary and Ectopic Adrenocorticotropic Hormone-Secreting Tumors

Endogenous Cushing’s syndrome (CS) is a rare neuroendocrine disorder characterized by either secondary cortisol increases due to an adrenocorticotropic hormone (ACTH)-secreting pituitary tumor (Cushing’s disease (CD)), an ACTH-secreting ...
Roman V. Kholodenko, Evgeniya V. Plaksina, Rustam N. Heydarov, Alina V. Matrosova, Olga O. Golounina, Maksim I. Sorokin, Sergey A. Roumiantsev, Maria V. Suntsova, Irina V. Kholodenko, Zhanna E. Belaya, Anton A. Buzdin, Galina A. Melnichenko, Vladimir P. Chekhonin, Liudmila Y. Rozhinskaya, Ekaterina V. Bondarenko   +14 more
core   +1 more source

Treatment of Canine Atopic Dermatitis: Updated Guidelines From the International Committee on Allergic Diseases of Animals (ICADA)

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller, Frane Banovic, Emmanuel Bensignor, Domenico Santoro, Tim Nuttall   +4 more
wiley   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source

24-hour adrenocorticotropic hormone (ACTH) concentration profiles

, 2019
Individual adrenocorticotropic hormone (ACTH) concentration profiles of 38 older subjects from the Leiden Longevity Study. Participants had a mean age (SD) of 65.1 (5.1) years with a range of 52-76 years.
Rudi G.J. Westendorp (711974), Hanno Pijl (123561), Diana van Heemst (7864793), Gerard J. Blauw (366082), Eline Slagboom (7865144), Ferdinand Roelfsema (175416), Evie van der Spoel (6835400), Steffy W. Jansen (772704), Abimbola A. Akintola (333226)   +8 more
core   +1 more source

Intramuscular pathways of maladaptation in overtraining syndrome

The Journal of Physiology, EarlyView.
Abstract figure legend The transition from adaptive overreaching to maladaptive overtraining and mechanisms through which excessive training load can lead to performance decline. Four interconnected pathophysiological domains are highlighted: neural fatigue, involving both central and peripheral components such as altered sensory feedback and reflex ...
Emily Shorter, Oscar Horwath, Sabrina Tzivia Barsky, Ferdinand von Walden, Johanna T. Lanner   +4 more
wiley   +1 more source