Results 21 to 30 of about 4,627 (243)

Successful application of technetium-99m-labeled octreotide acetate scintigraphy in the detection of ectopic adrenocorticotropin-producing bronchial carcinoid lung tumor: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction The diagnostic efficacy of somatostatin receptor scintigraphy labeling with 111 indium in the localization of tumors has been assessed in a limited number of patients with contradictory outcomes.
Fallahi Babak   +7 more
doaj   +1 more source

Deprenyl, an old drug with new anticancer potential: Mini review [PDF]

open access: yesarXiv, 2021
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv  

Neurobiology of Aggressive Behavior—Role of Autoantibodies Reactive With Stress-Related Peptide Hormones

open access: yesFrontiers in Psychiatry, 2019
Adrenocorticotropic hormone together with arginine vasopressin and oxytocin, the neuropeptides regulating the stress response and the hypothalamic-pituitary-adrenal axis activity, are known to modulate aggressive behavior.
Henning Vaeroy   +2 more
doaj   +1 more source

A unified model for the human response to lipopolysaccharide-induced inflammation [PDF]

open access: yesarXiv, 2022
This study develops a unified model predicting the whole-body response to endotoxin. We simulate dynamics using differential equations examining the response to a lipopolysaccharide (LPS) injection. The model tracks pro- and anti-inflammatory cytokines (TNF-$\alpha$, IL-6, IL-10), concentrations of corticotropin-releasing hormone (CRH ...
arxiv  

Mathematical Modelling of Hypothalamus-Pituitary-Adrenal Axis Dynamics: A Review, a Novel Approach, and Future [PDF]

open access: yesarXiv, 2023
A novel mathematical model for the hypothalamic pituitary adrenal (HPA) axis is proposed to comprehend the oscillations observed in hormone concentration and potential dysfunction within the HPA axis in stressful situation. This model integrates impact of hippocampal receptors on the secretion of corticotropin-releasing hormone (CRH), an additional ...
arxiv  

Adrenocorticotropic Hormone-Secreting Pheochromocytoma.

open access: yesInternal Medicine, 1998
A 41-year-old female had pheochromocytoma which secreted adrenocorticotropic hormone (ACTH). She was admitted to our hospital because of weight loss and excessive sweating. Not only urinary metanephrine but also plasma ACTH was extremely high. An abdominal echogram showed a cystic tumor in the left adrenal gland. An abdominal magnetic resonance imaging
Hajime Kitamura   +10 more
openaire   +4 more sources

A gain‐of‐function GRIA2 variant associated with neurodevelopmental delay and seizures: Functional characterization and targeted treatment

open access: yesEpilepsia, Volume 63, Issue 12, Page e156-e163, December 2022., 2022
Abstract α‐Amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid‐type glutamate receptors (AMPARs) are ligand‐gated cationic channels formed from combinations of GluA1‐4 subunits. Pathogenic variants of GRIA1–4 have been described in patients with developmental delay, intellectual disability, autism spectrum disorder, and seizures, with GRIA2 variants ...
Ian D. Coombs   +5 more
wiley   +1 more source

Isolated adrenocorticotropic hormone deficiency and thyroiditis associated with nivolumab therapy in a patient with advanced lung adenocarcinoma: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2019
Introduction Immune checkpoint inhibitors are a promising class of anticancer drugs. The clinical benefits afforded by immune checkpoint inhibitors can be accompanied by immune-related adverse events that affect multiple organs, and endocrine immune ...
Nobumasa Ohara   +8 more
doaj   +1 more source

Predictors of laminitis development in a cohort of nonlaminitic ponies

open access: yesEquine Veterinary Journal, Volume 55, Issue 1, Page 12-23, January 2023., 2023
Abstract Background Quantifying risk factors for laminitis development requires improvement. Objectives To identify the most useful physical examination, metabolic and management factors to predict laminitis development in client‐owned, nonlaminitic ponies. Study design Prospective cohort study.
Edward J. Knowles   +4 more
wiley   +1 more source

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