Results 21 to 30 of about 56,393 (264)

Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors [PDF]

open access: yes, 2016
PURPOSE: Subsets of pituitary tumors exhibit an aggressive clinical courses and recur despite surgery, radiation, and chemotherapy. Because modulation of the immune response through inhibition of T-cell checkpoints has led to durable clinical responses ...
Agar, Nathalie Y. R.   +13 more
core   +3 more sources

Neurobiology of Aggressive Behavior—Role of Autoantibodies Reactive With Stress-Related Peptide Hormones

open access: yesFrontiers in Psychiatry, 2019
Adrenocorticotropic hormone together with arginine vasopressin and oxytocin, the neuropeptides regulating the stress response and the hypothalamic-pituitary-adrenal axis activity, are known to modulate aggressive behavior.
Henning Vaeroy   +2 more
doaj   +1 more source

The relationship between liver function and neurophysiological factors in depressed individuals: a cross-sectional study using an integrated “East meets West” medicine approach

open access: yesFrontiers in Psychiatry, 2023
Introduction:Depression is a common mental disorder worldwide. The pathology of depression may involve the dysregulation of neurotransmitters and immunity and produce genetic and environmental effects.
Jiajia Ye   +8 more
doaj   +1 more source

Glucocorticoids rapidly inhibit oxytocin-stimulated adrenocorticotropin release from rat anterior pituitary cells, without modifying intracellular calcium transients [PDF]

open access: yes, 1993
Glucocorticoid hormones suppress the secretion of ACTH evoked by secretagogues such as CRF and arginine vasopressin. In this study, we investigated the effects of glucocorticoids on ACTH release induced by oxytocin (OT) and on intracellular free calcium ...
Dayanithi, G., Gratzl, Manfred, Link, H.
core   +1 more source

Homeostasis as the Mechanism of Evolution. [PDF]

open access: yes, 2015
Homeostasis is conventionally thought of merely as a synchronic (same time) servo-mechanism that maintains the status quo for organismal physiology. However, when seen from the perspective of developmental physiology, homeostasis is a robust, dynamic ...
Torday, John S
core   +2 more sources

Isolated adrenocorticotropic hormone deficiency and thyroiditis associated with nivolumab therapy in a patient with advanced lung adenocarcinoma: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2019
Introduction Immune checkpoint inhibitors are a promising class of anticancer drugs. The clinical benefits afforded by immune checkpoint inhibitors can be accompanied by immune-related adverse events that affect multiple organs, and endocrine immune ...
Nobumasa Ohara   +8 more
doaj   +1 more source

The role of hypothalamus-pituitary-adrenal (HPA)-like axis in inflammatory pilosebaceous disorders [PDF]

open access: yes, 2020
Skin is the largest peripheral endocrine organ and functions as a hormone target and endocrine gland. A cutaneous hypothalamus-pituitary-adrenal (HPA)-like axis enables the skin to respond to stress and regulates its steroidogenic activity.
Clark, Ashley K   +3 more
core  

Trilostane in dogs [PDF]

open access: yes, 2010
Over the last 10 years, trilostane, a competitive inhibitor of steroid synthesis, is being widely used for the treatment of canine hyperadrenocorticism.
Alenza   +59 more
core   +1 more source

Optimal management of seizures associated with tuberous sclerosis complex: current and emerging options. [PDF]

open access: yes, 2014
Seizures are clinically significant manifestations associated with 79%-90% of patients with tuberous sclerosis complex. Often occurring within the first year of life in the form of infantile spasms, seizures interfere with neuropsychiatric, social, and ...
Fallah, Aria, Wang, Shelly
core   +2 more sources

Effects of catecholamines on the lipolysis of two kinds of fat cells from adult rabbit

open access: yesJournal of Lipid Research, 1976
The administration of various catecholamines and adrenocorticotropic hormone to adult rabbit elevated plasma glycerol concentration. These catecholamines also induced the in vitro lipolysis of isolated interscapular fat cells but could not bring about ...
A Kumon, T Hara, A Takahashi
doaj   +1 more source

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