Results 61 to 70 of about 1,080,461 (263)

9388 Unusual Case Of Ectopic Adrenocorticotropic Hormone Syndrome Secondary To Non-small Cell Lung Cancer [PDF]

J Endocr Soc
Asieh TakallooBakhtiari, Gail Louise Nunlee-Bland, Vijaya Ganta, Anteneh Zenebe, Hadeel Abdalla, Abdelghaffar Mohamed Elobeid, Wolali Odonkor   +6 more
openalex   +2 more sources

Ectopic Adrenocorticotropic Hormone–Producing Renal Cell Carcinoma Causing Psychosis in a Patient With Birt-Hogg-Dubé Syndrome

Annals of Internal Medicine: Clinical Cases
This is, to our knowledge, the first-ever recorded case of Birt-Hogg-Dubé syndrome associated with an adrenocorticotropic hormone–secreting renal cell carcinoma.
Talal Alomar, Wishwdeep Dhillon, Rahul Mehan, Guangming Guo, Mohamad H. Horani   +4 more
doaj   +1 more source

Primary pigmented nodular adrenocortical disease presenting with a unilateral adrenocortical nodule treated with bilateral laparoscopic adrenalectomy: a case report

Journal of Medical Case Reports, 2010
Introduction Primary pigmented nodular adrenocortical disease is a rare cause of adrenocorticotropic hormone-independent Cushing's syndrome. We report an uncommon primary pigmented nodular adrenocortical disease case presenting with a unilateral ...
Kaltsas Gregory, Chrysikos Dimosthenis T, Markou Athina, Avlonitis Spiros, Pappa Theodora, Zografos George N, Aggeli Chrysanthi, Piaditis George   +7 more
doaj   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Adrenocorticotropic hormone gel for patients with non-infectious uveitis

American Journal of Ophthalmology Case Reports, 2019
Purpose: To describe the potential role of adrenocorticotropic hormone (ACTH) gel treatment in patients with chronic non-infectious uveitis. Observations: We report the clinical course of three patients with bilateral, non-infectious anterior and ...
Yael Sharon, David S. Chu
doaj   +1 more source

Risk factors for immediate remission after operation in patients with Cushing's disease

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To explore the preoperative factors affecting the immediate remission of Cushing's disease after transsphenoidal surgery. Methods A total of 420 patients with Cushing's disease (led by Dr.
ZHANG Wen⁃tai, WANG Ren⁃zhi, FENG Ming   +2 more
doaj   +1 more source

Isolated adrenocorticotropic hormone deficiency development during chemotherapy for gastric cancer: a case report

Journal of Medical Case Reports, 2014
IntroductionIsolated adrenocorticotropic hormone deficiency is an endocrinological disorder characterized by loss of adrenocorticotropic hormone and resultant adrenal insufficiency. Affected patients often present with fatigue, anorexia, and hyponatremia.
J. Kinoshita, S. Higashino, S. Fushida, K. Oyama, Toshifumi Watanabe, K. Okamoto, Keishi Nakamura, H. Takamura, I. Ninomiya, H. Kitagawa, T. Fujimura, T. Ohta   +11 more
semanticscholar   +1 more source

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal‐Weight Rats, Prevented by Perinatal Leptin Intake

Molecular Nutrition &Food Research, EarlyView.
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
Carmen García‐Ruano, Andrea Costa, Andreu Palou, Paula Oliver   +3 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Predicting Residual 21‐Hydroxylase Enzymatic Activity in Pediatric and Adult Congenital Adrenal Hyperplasia Patients: Towards Individualized Therapy

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Congenital adrenal hyperplasia (CAH) is a genetic disorder characterized by impaired cortisol production and consequent elevated adrenocorticotropic hormone (ACTH): CAH patients often require lifelong hydrocortisone therapy. Disease severity reflects residual 21‐hydroxylase enzyme activity, crucial for cortisol synthesis.
Davide Bindellini, Robin Michelet, Yersultan Mirasbekov, Qizong Lao, Charles Sukin, Wilhelm Huisinga, Deborah P. Merke, Charlotte Kloft   +7 more
wiley   +1 more source