Results 1 to 10 of about 556 (62)

Utilizing of Adsorptive Transfer Stripping Technique Brdicka Reaction for Determination of Metallothioneins Level in Melanoma Cells, Blood Serum and Tissues [PDF]

Sensors, 2008
In the paper we utilized the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothioneins (MT) in melanoma cells, animal melanoma tissues (MeLiM miniature pig) and blood serum of patients with ...
Rene Kizek, Vratislav Horak, Jan Strnadel, Libuse Trnkova, Grace J. Chavis, Richard Prusa, Jiri Kukacka, Vojtech Adam, Ivo Fabrik, Sona Krizkova   +9 more
doaj   +4 more sources

Zeptomole electrochemical detection of metallothioneins. [PDF]

PLoS ONE, 2010
BackgroundThiol-rich peptides and proteins possess a large number of biological activities and may serve as markers for numerous health problems including cancer. Metallothionein (MT), a small molecular mass protein rich in cysteine, may be considered as
Vojtech Adam, Jitka Petrlova, Joseph Wang, Tomas Eckschlager, Libuse Trnkova, Rene Kizek   +5 more
doaj   +1 more source

Possibilities of electrochemical techniques in metallothionein and lead detection in fish tissues

Czech Journal of Animal Science, 2007
In the present paper, we report on the use of adsorptive transfer stripping technique in connection with chronopotentiometric stripping analysis for metallothionein determination and of differential pulse anodic stripping voltammetry for lead detection ...
S. Křížková, O. Zítka, V. Adam, M. Beklová, A. Horna, Z. Svobodová, B. Sures, L. Trnková, L. Zeman, R. Kizek   +9 more
doaj   +1 more source

Beads Based Electrochemical Assay for Detection of Hemagglutinin Labeled by Two Different Types of Cadmium Quantum Dots

International Journal of Electrochemical Science, 2014
In this study it is described beads based isolation assay terminated by electrochemical analysis of hemagglutinin (HA) using two different cadmium quantum dots (QDs) labelled as CdS and CdTe.
Ludmila Krejcova, David Hynek, Roman Guran, Petr Michalek, Amitava Moulick, Pavel Kopel, Katerina Tmejova, Nguien Viet Hoai, Vojtech Adam, Jaromir Hubalek, Jindrich Kynicky, Rene Kizek   +11 more
doaj   +1 more source

Electrochemical Study of Doxorubicin Interaction with Different Sequences of Double Stranded Oligonucleotides, Part II

International Journal of Electrochemical Science, 2012
Interaction of low molecular weight compounds with DNA is one of general mechanisms utilized for an effective anticancer therapy. The anthracycline doxorubicin is one of the drugs that represent the compound with such effect.
David Hynek, Ludmila Krejcova, Ondrej Zitka, Vojtech Adam, Libuse Trnkova, Jiri Sochor, Marie Stiborova, Tomas Eckschlager, Jaromir Hubalek, Rene Kizek   +9 more
doaj   +1 more source

Femtogram Electroanalytical Detection of Prostatic Specific Antigen by Brdicka Reaction

International Journal of Electrochemical Science, 2012
Prostatic-specific antigen is considered as the best marker for prostate cancer. Due to the importance of PSA for diagnostic purposes it is not surprising that there are tested and optimized various methods for its determination.
David Hynek, Sona Krizkova, Ludmila Krejcova, Jaromir Gumulec, Marketa Ryvolova, Natalia Cernei, Michal Masarik, Vojtech Adam, Libuse Trnkova, Marie Stiborova, Tomas Eckschlager, Jaromir Hubalek, Rene Kizek   +12 more
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Electrochemical Study of Doxorubicin Interaction with Different Sequences of Single Stranded Oligonucleotides, Part I

International Journal of Electrochemical Science, 2012
Doxorubicin is a known anticancer drug intercalating into dsDNA. The mechanism of interaction of doxorubicin with ssDNA is not clear. In this study, adsorptive transfer stripping technique coupled with square wave voltammetry was used for studying of ...
David Hynek, Ludmila Krejcova, Ondrej Zitka, Vojtech Adam, Libuse Trnkova, Jiri Sochor, Marie Stiborova, Tomas Eckschlager, Jaromir Hubalek, Rene Kizek   +9 more
doaj   +1 more source

Phytochelatin Modified Electrode Surface as a Sensitive Heavy- Metal Ion Biosensor

Sensors, 2005
Electrochemical biosensors have superior properties over other existingmeasurement systems because they can provide rapid, simple and low-cost on-fielddetermination of many biological active species and a number of dangerous pollutants.
Rene Kizek, Jan Vitecek, Frantisek Jelen, Libuse Trnkova, Bernd Sures, David Potesil, Jitka Petrlova, Josef Zehnalek, Vojtech Adam Adam   +8 more
doaj   +1 more source

Electrochemical Behaviour of Native and Denatured β-Sheet Breaker Prion Protein

International Journal of Electrochemical Science, 2012
Prion diseases are fatal neurodegenerative and infectious disorders of humans and animals, characterized by structural transition of the host-encoded cellular prion protein (PrPC) into the aberrantly folded pathologic isoform PrPSc.
Pavlina Sobrova, Marketa Ryvolova, David Hynek, Vojtech Adam, Jaromir Hubalek, Rene Kizek   +5 more
doaj   +1 more source

Spectrometric and Voltammetric Analysis of Urease – Nickel Nanoelectrode as an Electrochemical Sensor

Sensors, 2007
Urease is the enzyme catalyzing the hydrolysis of urea into carbon dioxide andammonia. This enzyme is substrate-specific, which means that the enzyme catalyzes thehydrolysis of urea only.
Rene Kizek, Josef Zehnalek, Martin Adamek, Katerina Klosova, Ales Horna, Libuse Trnkova, Michal Masarik, Dalibor Huska, Olga Krystofova, Vojtech Adam, Jan Hradecky, Jaromir Hubalek   +11 more
doaj   +1 more source