Results 1 to 10 of about 186 (89)

A Determination of Metallothionein in Larvae of Freshwater Midges (Chironomus riparius) Using Brdicka Reaction [PDF]

Sensors, 2008
Among wide spectrum of biomolecules induced by various stress factors low molecular mass protein called metallothionein (MT) is suitable for assessment of the heavy metal environmental pollution.
Rene Kizek, Libuse Trnkova, Vojtech Adam, Klara Hilscherova, Zuzana Ruferova, Ivo Fabrik   +5 more
doaj   +5 more sources

Utilizing of Adsorptive Transfer Stripping Technique Brdicka Reaction for Determination of Metallothioneins Level in Melanoma Cells, Blood Serum and Tissues [PDF]

Sensors, 2008
In the paper we utilized the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothioneins (MT) in melanoma cells, animal melanoma tissues (MeLiM miniature pig) and blood serum of patients with ...
Rene Kizek, Vratislav Horak, Jan Strnadel, Libuse Trnkova, Grace J. Chavis, Richard Prusa, Jiri Kukacka, Vojtech Adam, Ivo Fabrik, Sona Krizkova   +9 more
doaj   +5 more sources

Femtogram Electroanalytical Detection of Prostatic Specific Antigen by Brdicka Reaction

International Journal of Electrochemical Science, 2012
Prostatic-specific antigen is considered as the best marker for prostate cancer. Due to the importance of PSA for diagnostic purposes it is not surprising that there are tested and optimized various methods for its determination.
David Hynek, Sona Krizkova, Ludmila Krejcova, Jaromir Gumulec, Marketa Ryvolova, Natalia Cernei, Michal Masarik, Vojtech Adam, Libuse Trnkova, Marie Stiborova, Tomas Eckschlager, Jaromir Hubalek, Rene Kizek   +12 more
doaj   +2 more sources

An adsorptive transfer technique coupled with brdicka reaction to reveal the importance of metallothionein in chemotherapy with platinum based cytostatics. [PDF]

Int J Mol Sci, 2010
The drugs based on platinum metals represent one of the oldest, but also one of the most effective groups of chemotherapeutic agents. Thanks to many clinical studies it is known that resistance of tumor cells to drugs is a frequent cause of chemotherapy failure.
Krizkova S, Fabrik I, Huska D, Adam V, Babula P, Hrabeta J, Eckschlager T, Pochop P, Darsova D, Kukacka J, Prusa R, Trnkova L, Kizek R.   +12 more
europepmc   +4 more sources

Tissue specific electrochemical fingerprinting. [PDF]

PLoS ONE, 2012
BACKGROUND: Proteomics and metalloproteomics are rapidly developing interdisciplinary fields providing enormous amounts of data to be classified, evaluated and interpreted. Approaches offered by bioinformatics and also by biostatistical data analysis and
Pavlina Sobrova, Lenka Vyslouzilova, Olga Stepankova, Marketa Ryvolova, Jiri Anyz, Libuse Trnkova, Vojtech Adam, Jaromir Hubalek, Rene Kizek   +8 more
doaj   +2 more sources

Study of Interactions between Metallothionein and Cisplatin by using Differential Pulse Voltammetry Brdicka´s reaction and Quartz Crystal Microbalance [PDF]

Sensors, 2009
Treatment strategies for tumour diseases are progressively focusing on personalization of medicine. However, this focus requires methods revealing the early general biological mechanisms, including the formation anti-cancer drugs’ resistance.
Húska, Dalibor, Fabrik, Ivo, Baloun, Jiří, Adam, Vojtěch, Masařík, Michal, Hubálek, Jaromír, Vašků, Anna, Trnková, Libuše, Horna, Aleš, Zeman, Ladislav, Kizek, René   +10 more
doaj   +5 more sources

An Electrochemical Detection of Metallothioneins at the Zeptomole Level in Nanolitre Volumes [PDF]

Sensors, 2008
An Electrochemical Detection of Metallothioneins at the Zeptomole Level in Nanolitre VolumesWe report on improvement of the adsorptive transfer stripping technique (AdTS) coupled with the differential pulse voltammetry Brdicka reaction to determine a ...
Rene Kizek, Libuse Trnkova, Ivo Fabrik, Jiri Baloun, Vojtech Adam   +4 more
doaj   +2 more sources

Study of Metallothionein Role in Spinocellular Carcinoma Tissues of Head and Neck Tumours using Brdicka Reaction

International Journal of Electrochemical Science, 2012
Malignant tumours of head and neck localisation represent serious health problem. All over the world, there is about 650 000 of patients who fall ill with head and neck carcinoma per year. Treatment of this malignity is based especially on the well-timed
Jiri Sochor, David Hynek, Ludmila Krejcova, Ivo Fabrik, Sona Krizkova, Jaromir Gumulec, Vojtech Adam, Petr Babula, Libuse Trnkova, Marie Stiborova, Jaromir Hubalek, Michal Masarik, Hana Binkova, Tomas Eckschlager, Rene Kizek   +14 more
doaj   +2 more sources

Development and Evaluation of Copper Electrodes, Modified with Bimetallic Nanoparticles, to be Used as Sensors of Cysteine-Rich Peptides Synthesized by Tobacco Cells Exposed to Cytotoxic Levels of Cadmium [PDF]

Molecules, 2019
We report on two new electrochemical sensors which, coupled to differential pulse voltammetry, constitutes a useful tool for diagnosis of heavy metal pollution.
Carlos Velasco-Medina, Patricio J. Espinoza-Montero, Marjorie Montero-Jimenez, José Alvarado, Mónica Jadán, Patricio Carrera, Lenys Fernandez   +6 more
doaj   +2 more sources

Effect of Cadmium Chloride on Metallothionein Levels in Carp [PDF]

Sensors, 2009
Due to anthropogenic activities, heavy metals still represent a threat for various trophic levels. If aquatic animals are exposed to heavy metals, we can obviously observe considerable toxicity.
Jana Kovarova, Rene Kizek, Vojtech Adam, Danka Harustiakova, Olga Celechovska, Zdenka Svobodova   +5 more
doaj   +2 more sources