Results 41 to 50 of about 6,693,207 (250)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Adult onset Still’s disease: a diagnostic challenge
, 2018 <p class="abstract"><span lang="EN-IN">Adult Still’s disease (ASD) is a systemic inflammatory disorder of unknown etiology, typically characterized by a clinical triad of daily spiking high fevers, evanescent rash, and arthritis.
Rahul Jain, V. K. Joglekar, Kriti Jain
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
ADULT-ONSET STILL’S DISEASE: ASPECTS OF THE HEMATOLOGY CLINIC
, 2019 The analysis of literature data on modern approaches in the diagnosis and treatment of adult-onset Still’s disease has been performed. A clinical case of Still’s disease associated with lymphadenopathy syndrome was demonstrated.
I. I. Mulina +6 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
BMC Musculoskeletal DisordersBackground Adult-onset still’s disease and septic arthritis share similar symptoms—fever, joint pain, and limited mobility—making postoperative diagnosis difficult after combined anterior cruciate ligament and posterior cruciate ligament reconstruction ...
Zenan Tian +11 more
doaj +1 more source
Adult-onset Still’s disease triggered by pregnancy [PDF]
, 2019 Adult-onset Still’s disease (AOSD) is an inflammatory disorder with arthritis, quotidian fever, evanescent rash, elevated white cell count, elevated ferritin, and abnormal liver function tests.
Abdulkarim, Saleem +2 more
core
, 2014 Adult-onset Still’s disease (AOSD) is a chronic disease marked by seronegative arthritis accompanied by the involvement of the internal organs. Typical symptoms including fever, arthritis, joint pain, and a distinctive salmon-colored rash, often ...
Paweł Hrycaj, Dorota Cieślak
core +1 more source
Adult-onset Still’s disease: pathogenesis, symptoms, diagnostics and treatment. [PDF]
, 2021 Adult-onset Still’s disease (AoSD) is a rare but clinically well-known, polygenic, systemic autoinflammatory disease. Typically this disease occurs by four main symptoms: spiking fever ≥ 39 °C, arthralgia or arthritis, skin rash, and leukocytosis (≥ 10 ...
Kaušaitė, Dominyka,
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source