Results 101 to 110 of about 10,032,022 (290)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Journal of Research in Education Sciences隨著臺灣即將進入超高齡社會，如何讓屆退民眾預先做好退休準備、確保退休生活品質，是當前臺灣高齡社會一項重要課題。本研究目的在以退休前10年的公教人員為研究對象，透過翻轉教學實驗瞭解學習需求與實際學習效果的差距，再藉由退休準備教育課程需求現況調查，瞭解不同需求課程實施翻轉教學策略的成效，進而調整出適合屆退族群的退休課程與教學策略，以培養其充足的退休知識與應用能力，做好前瞻因應的退休準備。本研究採用問卷調查法進行需求調查，研究設計採分層隨機抽樣，研究工具「臺灣退休準備教育課程需求指標 ...
胡夢鯨 Menq-Jing Hwu +3 more
doaj +1 more source
Avoiding pitfalls in the next International Conference on Adult Education (CONFINTEA): Lessons on financing adult education from Belém. [PDF]
Int Rev Educ, 2022 Archer D.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Journal of Research in Education Sciences青銀世代對數位遊戲的使用動機具差異性，而數位遊戲的開發或設計往往無法為所有年齡層量身定做，例如長者對於規則太複雜、時間太緊湊的遊戲設計有負面的認知，但年輕人反而追求遊戲的效率。此外，過去探討不同世代數位遊戲設計及功能評估的研究，大多為受試者自陳、觀察和訪談方法蒐集主動意識層面的資料，較少透過語意聯想這類的結果探究。 據此，本研究欲以數位遊戲認知的語意聯想測驗（Word Association Test, WAT）蒐集多元的資料以探討世代間之異同。本研究以便利取樣招募178位不同年齡層的對象 ...
劉智淇 Chih-Chi Liu +1 more
doaj +1 more source
Pedagogies of song: Music as/in adult education
, 2008 We argue for music's power in promoting adult learning about democracy and social justice. Drawing from the literature and our own experiences conducting and studying music, we focus on community choirs to illustrate how the unique properties and ...
Fenwick, Tara +1 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Children’s Voice in “Nurseries of Democracy“. Participation in Early Childhood Institutions
Social Work and Society, 2018 According to the UN Conventions on the Rights of the Child all children have a right to participation. This UN Convention has influenced professionals and policy-makers worldwide.
Alexandra Klein, Sandra Landhäußer
doaj
Who moved my old cheese? Implications of COVID 19 to teaching and learning in Southern Africa
Journal of Teaching and Learning with Technology, 2021 This reflective essay seeks to share the authors’ thoughts and feelings on the impact of COVID 19 on the general teaching and learning strategies, theories and practices in the small kingdom of Eswatini in Southern Africa. Coming from varying backgrounds
Selloane Pitikoe +4 more
doaj
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source