Results 111 to 120 of about 1,014,159 (263)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Beyond the classroom: following the destination of Haramaya University graduates in the real world, Ethiopia

open access: yesCogent Education
This study delves into the perspectives of Haramaya University (HU) graduates regarding their competence, employment prospects, and career advancement.
Yilfashewa Seyoum   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Economic rationality and educational realities: efficiency effects of institutional mergers in German adult education (1995–2017)

open access: yesCogent Education
The policy of merging education institutions to improve efficiency and reduce public expenditure has gained popularity in many European countries. However, although this phenomenon is observed in adult education, there is currently a paucity of evidence ...
Nicolas Echarti   +2 more
doaj   +1 more source

Positive Adult Education, Learned Helplessness and the Pygmalion Effect. [PDF]

open access: yesInt J Environ Res Public Health, 2022
Cobos-Sanchiz D   +3 more
europepmc   +1 more source

Adult Education

open access: yesThe American Journal of Nursing, 1927
"General bibliography": p. 337-338; "Readings" at end of each chapter except the last. ; Mode of access: Internet.
openaire   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Development and Evaluation of a Shared Decision‐Making Patient Decision Aid for Dental Clinic Care: A Mixed‐Methods Study

open access: yesHealth Science Reports
Background and Aims Shared decision‐making (SDM) is increasingly recognized as a core element of patient‐centered dental care, promoting collaboration between clinicians and patients to ensure that treatment decisions reflect both clinical evidence and ...
Ching‐Wen Liu, Hsiao‐Hui Jung
doaj   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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