Results 71 to 80 of about 12,947,086 (290)

Adult health returns to education by key childhood social and economic indicators: Results from representative European data

open access: yesSSM: Population Health, 2017
In the United States, associations between attained education and adult health typically are larger for those from disadvantaged childhood backgrounds.
Matthew A. Andersson, Kenneth Vaughan
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Evidence-based policy-making: the usability of the Eurostat Adult Education Survey [PDF]

open access: yesInternational Journal of Lifelong Education, 2014
This article reflects on European education policy which is driven by benchmarks and indicators. While the European benchmark on adult lifelong learning participation—15% to be achieved by 2020—is measured by the Labour Force Survey, the Eurostat Adult Education Survey (AES) was designed to better understand the topic of adult lifelong learning ...
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Accountability practices in adult education: Insights from actor-network theory

open access: yes, 2010
Accountability mechanisms in adult education, their constitution and their effects, are of increasing concern in an era threatening massive reductions to resources for adult education activity.
Fenwick, Tara
core  

A European study investigating adult numeracy education

open access: yesEuropean Journal for Research on the Education and Learning of Adults
Numeracy is a critical competency needed by adults to navigate their way through tasks in their personal and professional lives. Hence, it is critical that efforts are made to identify and address challenges that prevent adults from developing the ...
Niamh O'Meara   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

An Unrealistic ‘Mission Impossible’? Surveying Principals’ Interpretations and Local Solutions for L2-mediated EFL in Finnish Adult Basic Education

open access: yesNJES: Nordic Journal of English studies
Finnish Adult Basic Education (ABE) comprises primary and lower secondary education designed to improve adult immigrants’ participation. Completing the entire syllabus and graduating with a Finnish basic education certificate is helpful for many adult ...
Antti Suomela
doaj   +1 more source

Current state of Czech andragogy [PDF]

open access: yesPedagogická Orientace, 2010
The survey article should serve as an information for educationists about thesituation of andragogy (theory and research of adult education) in the Czech Republic.First, a brief explanation is presented based on definitions of andragogy and its ...
Jan Průcha
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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