Results 81 to 90 of about 12,947,086 (290)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Adult education in Malta : challenges and prospects [PDF]

open access: yes, 2012
Lifelong learning has long been a topic of discussion in Malta but, as this article shows, barriers to participation continue to exist. This article outlines the historical and economic changes that have led Malta to its present situation where adult ...
Mayo, Peter
core   +1 more source

Nonresponse in PIAAC Germany

open access: yesMethoden, Daten, Analysen, 2014
Nonresponse is of concern for the quality of survey data, because it may introduce bias into the collected sample. To date, only few studies deal with nonresponse in skills or educational surveys.
Susanne Helmschrott, Silke Martin
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Was it worth it? A comparison of the role of adult education and training in the labour market insertion and progress of men and women in the West of Scotland: results of qualitative research [PDF]

open access: yes, 2000
Despite a number of relevant longitudinal studies carried out in Sweden, Finland, Norway and the United States of America, there is a relative paucity of research into the long-term outcomes of adult return to learning.
Clayton, P.
core   +1 more source

Statistical Survey of Non-Formal Education [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2012
focused on a programme within a regular education system. Labour market flexibility and new requirements on employees create a new domain of education called non-formal education.
Ondřej Nývlt
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Biology - Stage 2: Laboratory Rules

open access: yes, 2011
The Institute for Adult Education in Tanzania developed a Multimedia Strategy to assist them to achieve its Mission ‘to design and implement quality adult and continuing education and training programmes that will enable its learners to acquire knowledge

core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy