Results 81 to 90 of about 12,947,086 (290)
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Adult education in Malta : challenges and prospects [PDF]
Lifelong learning has long been a topic of discussion in Malta but, as this article shows, barriers to participation continue to exist. This article outlines the historical and economic changes that have led Malta to its present situation where adult ...
Mayo, Peter
core +1 more source
Nonresponse is of concern for the quality of survey data, because it may introduce bias into the collected sample. To date, only few studies deal with nonresponse in skills or educational surveys.
Susanne Helmschrott, Silke Martin
doaj +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Was it worth it? A comparison of the role of adult education and training in the labour market insertion and progress of men and women in the West of Scotland: results of qualitative research [PDF]
Despite a number of relevant longitudinal studies carried out in Sweden, Finland, Norway and the United States of America, there is a relative paucity of research into the long-term outcomes of adult return to learning.
Clayton, P.
core +1 more source
Statistical Survey of Non-Formal Education [PDF]
focused on a programme within a regular education system. Labour market flexibility and new requirements on employees create a new domain of education called non-formal education.
Ondřej Nývlt
doaj
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Biology - Stage 2: Laboratory Rules
The Institute for Adult Education in Tanzania developed a Multimedia Strategy to assist them to achieve its Mission ‘to design and implement quality adult and continuing education and training programmes that will enable its learners to acquire knowledge
core +1 more source
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source

