Results 141 to 150 of about 110,453 (370)

Timing is everything: The effect of early‐life seizures on developing neuronal circuits subserving spatial memory

open access: yesEpilepsia Open, EarlyView.
Abstract Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus‐dependent spatial memory is not innate and emerges during development in both humans and rodents.
Gregory L. Holmes
wiley   +1 more source

Adult Hippocampal Neurogenesis and Memory [PDF]

open access: yesInternational Journal of Advanced Biological and Biomedical Research, 2017
Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia).
openaire   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Adolescent but not adult-born neurons are critical for susceptibility to chronic social defeat

open access: yesFrontiers in Behavioral Neuroscience, 2014
Recent evidence implicates adult hippocampal neurogenesis in regulating behavioral and physiologic responses to stress. Hippocampal neurogenesis occurs across the lifespan, however the rate of cell birth is up to 300% higher in adolescent mice compared ...
Greer S Kirshenbaum   +4 more
doaj   +1 more source

Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation. [PDF]

open access: yes, 2018
Interactions between EphB4 receptor tyrosine kinases and their membrane-bound ephrin-B2 ligands on apposed cells play a regulatory role in neural stem cell differentiation.
Chung, Jean   +6 more
core   +2 more sources

P2X7 receptor signaling during adult hippocampal neurogenesis

open access: yesNeural Regeneration Research, 2019
Neurogenesis is a persistent and essential feature of the adult mammalian hippocampus. Granular neurons generated from resident pools of stem or progenitor cells provide a mechanism for the formation and consolidation of new memories. Regulation of hippocampal neurogenesis is complex and multifaceted, and numerous signaling pathways converge to ...
Leeson, H   +5 more
openaire   +4 more sources

Faecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies

open access: yesEuropean Eating Disorders Review, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen   +6 more
wiley   +1 more source

Involvement of Adult Hippocampal Neurogenesis in Learning and Forgetting

open access: yesNeural Plasticity, 2015
Adult hippocampal neurogenesis is a process involving the continuous generation of newborn neurons in the hippocampus of adult animals. Mounting evidence has suggested that hippocampal neurogenesis contributes to some forms of hippocampus-dependent ...
Suk-yu Yau, Ang Li, Kwok-Fai So
doaj   +1 more source

Divergent Roles of Central Serotonin in Adult Hippocampal Neurogenesis

open access: yesFrontiers in Cellular Neuroscience, 2017
The central serotonin (5-HT) system is the main target of selective serotonin reuptake inhibitors (SSRIs), the first-line antidepressants widely used in current general practice.
Ning-Ning Song   +12 more
doaj   +1 more source

Methods to study adult hippocampal neurogenesis in humans and across the phylogeny [PDF]

open access: bronze, 2022
Julia Terreros‐Roncal   +7 more
openalex   +1 more source

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