Results 91 to 100 of about 4,444,458 (302)

Older Adult Residents' Perceptions of Daily Lives in Nursing Homes

Journal of Nursing Scholarship, 2017
Purpose This study aimed to explore older adults’ perceptions of their daily lives in South Korean nursing homes. Design We employed a qualitative descriptive study using semistructured interviews.
E. Cho, Hyejin Kim, Jeongah Kim, Kyongeun Lee, S. Meghani, S. Chang   +5 more
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Prevalence and influencing factors of regular physical activity among community-dwelling adults in Shaanxi province, 2018: an analysis of surveillance data

Zhongguo gonggong weisheng
ObjectiveTo investigate the prevalence of regular physical activity and its influencing factors among adult community residents in Shaanxi province, providing a reference for behavioral interventions targeting the general population, especially key ...
Yali TAO, Rina SA, Weihua WANG, Meng WU, Rong LIU, Lin QIU   +5 more
doaj   +1 more source

Eating Out-of-Home in Adult Residents in Shanghai and the Nutritional Differences among Dining Places

Nutrients, 2018
Background: With the rapid development of Shanghai’s economy, diet habits have undergone great changes. The study aimed to examine the situation of out-of-home (OH) eating in Shanghai adults and the nutrition characteristics of eating in different dining
J. Zang, B. Luo, Yaping Wang, Zhenni Zhu, Zhengyuan Wang, Xin He, Wenjing Wang, Yan Guo, Xiao Chen, Chunfang Wang, Changyi Guo, S. Zou, X. Jia, Fan Wu   +13 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Effects of aircraft noise on annoyance, sleep disorders, and blood pressure among adult residents near the Orio al Serio International Airport (BGY), Italy

La Medicina del lavoro, 2018
Background: Aircraft noise may cause several non-auditory health effects, including annoyance, sleep disorders, hypertension, cardiovascular diseases, and impaired cognitive skills in children.
M. Carugno, P. Imbrogno, A. Zucchi, R. Ciampichini, C. Ţereanu, G. Sampietro, G. Barbaglio, B. Pesenti, F. Barretta, P. Bertazzi, A. Pesatori, D. Consonni   +11 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Health utility value and its influencing factors among adult residents in Zhejiang province: a cross-sectional study using Shapley value decomposition analysis

Zhongguo gonggong weisheng
ObjectiveTo understand the health utility value and its influencing factors among adult residents in Zhejiang province, and to provide a reference for health policy formulation and evaluation.
Pinyuan DAI, Xiaoyan ZHOU, Hao WANG, Weiwei GONG, Jin PAN, Yunqi GUAN, Jieming ZHONG, Na LI   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source