Results 61 to 70 of about 667,957 (260)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PARENTING SELF-PERCEPTION: A COMPARATIVE STUDY OF TEENAGE AND EMERGING ADULT MOTHERS IN WEST JAVA
Jurnal Ilmu Keluarga dan KonsumenSome studies have shown differences in parenting practices between teenage and emerging adult mothers; however, not all research has found this to be the case.
Rini Hildayani +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Perceptions du rôle de l’interprète en contexte de formation internationale
Studia Romanica PosnaniensiaThis study explores the presence of community interpreters in lifelong learning contexts where adult learners engage in international education. It aims to uncover how adult learners perceive interpreters’ roles in educational settings through an online ...
Justyna Woroch
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The roles of NANOG in tumorigenesis
Molecular & Cellular Oncology, 2018 The pluripotency factor Nanog is highly expressed in pluripotent stem cells and certain adult stem cells, but is not expressed in normal adult cells. However, Nanog is frequently overexpressed in human cancers.
Jinchul Kim, Stefan Yu, Yang Xu
doaj +1 more source
THE REALITIES OF ORPHANED CHILDREN LIVING IN CHILD-HEADED HOUSEHOLDS
Social Work/Maatskaplike Werk, 2012 The HIV and AIDS epidemic has drastically changed the world in which children live in (Gruskin & Tarantola in Foster, Levine & Williamson, 2005:135). As a leading cause of adult mortality, the epidemic has led to many children becoming orphans worldwide.
Assim Hashim Alpaslan
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Associations of adult roles and minority stressors with trajectories of alcohol dependence symptoms throughout adulthood among sexual minority women. [PDF]
Psychol Addict Behav, 2023 Talley AE +5 more
europepmc +1 more source