Results 91 to 100 of about 235,905 (295)

Predictive values of early parental loss and psychopathological risk for physical problems in early adolescents [PDF]

open access: yes, 2018
Background: Several studies have suggested that the early loss of parents is a potentially traumatic experience, exposing adolescents to a higher risk for the onset of psychopathological symptoms.
Ballarotto, Giulia   +5 more
core   +2 more sources

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

open access: yesAdvanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu   +6 more
wiley   +1 more source

Risk Factors for Love Addiction in a Sample of Young Adult Students: A Multiple Mediation Model Exploring the Role of Adult Attachment, Separation Anxiety, and Defense Mechanisms

open access: yesBehavioral Sciences
In certain situations, romantic engagement with a partner can have detrimental effects on an individual’s well-being and overall health, exhibiting features attributable to addictive behaviors. Considering the clinical significance of this phenomenon and
Eleonora Topino   +3 more
doaj   +1 more source

The mental health of children and adolescents: report on the second Australian child and adolescent survey of mental health and wellbeing [PDF]

open access: yes, 2015
FOREWORD This report provides compelling reading for everyone interested in the health and wellbeing of Australian children and adolescents. Based on a survey conducted in the homes of over 6,300 families with children and/or adolescents aged 4 to 17 ...
David Lawrence   +6 more
core  

Corticotropin-releasing hormone as the homeostatic rheostat of feto-maternal symbiosis and developmental programming In utero and neonatal life [PDF]

open access: yes, 2017
A balanced interaction between the homeostatic mechanisms of mother and the devel- oping organism during pregnancy and in early neonatal life is essential in order to ensure optimal fetal development, ability to respond to various external and internal ...
Alcantara-Alonso   +114 more
core   +3 more sources

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

open access: yesAdvanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai   +13 more
wiley   +1 more source

Psychological screening of adults and young people following the Manchester Arena incident

open access: yesBJPsych Open, 2019
BackgroundTerrorist attacks have increased globally since the late 1990s with clear evidence of psychological distress across both adults and children and young people (CYP). After the Manchester Arena terrorist attack, the Resilience Hub was established
Paul French   +8 more
doaj   +1 more source

With a little help from FUN FRIENDS young children can overcome anxiety [PDF]

open access: yes, 2014
This paper highlights resilience as a key concept when working with young children to improve their emotional wellbeing and reduce anxieties. Supporting children aged 4-7 years with anxiety is a significant area of advancement in terms of therapeutic ...
Carlyle, Donna
core  

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Early Relationships, Pathologies of Attachment, and the Capacity to Love [PDF]

open access: yes, 2018
Psychologists often characterize the infant’s attachment to her primary caregiver as love. Philosophical accounts of love, however, tend to speak against this possibility.
Wonderly, Monique
core   +1 more source

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