Results 91 to 100 of about 820,702 (356)

Possible Therapeutic Effect of Ghrelin and Exosomes Derived from Mesenchymal Stem Cells on Induced Chronic Pancreatitis of Adult Albino Rats (Histological and Immunohistochemical Study) [PDF]

, 2022
Walaa Attaia, Mohammed Yousef, Nahla El-Eraky El-Azab, Nessrein Salem, S Bansod, A Khurana, C Godugu, T Napolitano, S Silvano, A Vieira, S Balaji, A Garrido-Utrilla, M Friano, M Tkach, C Thry, M Colombo, G Raposo, C Thry, S El Andaloussi, I Mger, X Breakefield, M Wood, M Zhang, X Zang, M Wang, Z Li, M Qiao, H Hua, E Eltantaway, G Khalaf, G Hamam, C Tmer, H Bilgin, B Obay, H Diken, E Tademir, A ermet, N El-Azab, A El-Mahalawaya, O Mostafa, D Sabry, R Mohamady, O Mohamed, L Seys, F Verhamme, A Schinwald, H Hammad, D Cunoosamy, D Mason, J Cordell, P Gaulard, A Tse, M Brown, C Kwon, J Cho, S Choi, K Ko, T H; Tirkes, M Gromski, E Moustafa, F Moawed, G Abdel-Hamid, S Sharma, S Rana, S Rana, D Bhasin, R Nada, S Malhotra, S Nadella, V Ciofoaia, H Cao, B Kallakury, R Tucker, J Smith, G Soliman, W Ibrahim, H Abdallah, G Biczo, E Vegh, N Shalbueva, O Mareninova, J Elperin, E Lotshaw, M Manohar, A Verma, S Venkateshaiah, A Mishra, A Lugea, L Nan, S French, J Bezerra, A Gukovskaya, S Pandol, P Hegyi, T Takcs, L Tiszlavicz, L Czak, J Lonovics, Z Warzecha, P Ceranowicz   +99 more
openalex   +1 more source

Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]

, 2011
In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo, Fera, Stefania, Grisanti, Laura, Lucia Scaldaferri, Maria, Sanchez, Massimo, Stefanini, Mario, Vicini, Elena   +6 more
core   +2 more sources

Adult neural stem cell plasticity

Neural Regeneration Research, 2019
Stem cells derived from adult tissues have long been considered multipotent, able to differentiate into a limited number of cell types found in their tissue of origin. Embryonic stem cells, in contrast, are pluripotent, which may differentiate into almost all cell types.
Sandquist, Elizabeth, Sakaguchi, Donald
openaire   +4 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Generation of Human Epidermis-Derived Mesenchymal Stem Cell-like Pluripotent Cells and their reprogramming in mouse chimeras [PDF]

, 2011
Stem cells can be derived from the embryo (embryonic stem cells, ESCs), from adult tissues (adult stem cells, ASCs), and by induction of fibroblasts (induced pluripotent stem cells, iPSs).
Bing Huang, Jian Ge, JianFa Huang, Jie Yu, KaiJing Li, LiPing Guan, LiPing Lin, Min Zhang, QianYing Gao, ShaoChun Lin, Ting Luo, WeiHua Li, WenCong Wang, WenXin Zhang, XiaoPing Xu, XiGu Chen, XinMing Song, XinTao Huang, YiChi Zhang, YongLiang Lin, YongPing Li, ZhiChong Wang   +21 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Primate Primordial Germ Cells Acquire Transplantation Potential by Carnegie Stage 23. [PDF]

, 2017
Primordial germ cells (PGCs) are the earliest embryonic progenitors in the germline. Correct formation of PGCs is critical to reproductive health as an adult.
Chen, Di, Clark, Amander T, Gkountela, Sofia, Hennebold, Jon D, Liu, Wanlu, Orwig, Kyle E, Sosa, Enrique, Sukhwani, Meena   +7 more
core   +2 more sources

Stem Cells: Adult

, 2015
This entry focuses on some of the core ethical issues arising from human adult stem cell research. It begins with a brief exploration of the history and science behind adult stem cell research. It then addresses three main ethical concerns about adult stem cell use, namely, the question of whether research on human embryonic stem cells should be ...
openaire   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The TGFβ type I receptor kinase inhibitor vactosertib in combination with pomalidomide in relapsed/refractory multiple myeloma: a phase 1b trial

Nature Communications
Functional blockade of the transforming growth factor-beta (TGFβ) signalling pathway improves the efficacy of cytotoxic and immunotherapies. Here, we conducted a phase 1b study (ClinicalTrials.gov., NCT03143985) to determine the primary endpoints of ...
Ehsan Malek, Priyanka S. Rana, Muthulekha Swamydas, Michael Daunov, Masaru Miyagi, Elena Murphy, James J. Ignatz-Hoover, Leland Metheny, Seong Jin Kim, James J. Driscoll   +9 more
doaj   +1 more source